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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 8643 |
Name | PTCH2 |
Synonym | PTC2;patched 2;PTCH2;patched 2 |
Definition | patched homolog 2|protein patched homolog 2 |
Position | 1p34.1 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | "Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32." |
| More detail of all 1 literatures about PTCH2 | |
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Pathways and Diseases |
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Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Signaling events mediated by the Hedgehog family;PID Curated;200144 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Hedgehog signaling pathway;KEGG PATHWAY;hsa04340 |
Disease | Basal cell carcinoma, somatic;OMIM |
Disease | Medulloblastoma;OMIM |
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External Links |
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Links to Entrez Gene | 8643 |
Links to all GeneRIF Items | 8643 |
Links to iHOP | 8643 |
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Sequence Information |
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Nucleotide Sequence |
>8643 : length: 3441 atgactcgatcgccgcccctcagagagctgcccccgagttacacacccccagctcgaacc gcagcaccccagatcctagctgggagcctgaaggctccactctggcttcgtgcttacttc cagggcctgctcttctctctgggatgcgggatccagagacattgtggcaaagtgctcttt ctgggactgttggcctttggggccctggcattaggtctccgcatggccattattgagaca aacttggaacagctctgggtagaagtgggcagccgggtgagccaggagctgcattacacc aaggagaagctgggggaggaggctgcatacacctctcagatgctgatacagaccgcacgc caggagggagagaacatcctcacacccgaagcacttggcctccacctccaggcagccctc actgccagtaaagtccaagtatcactctatgggaagtcctgggatttgaacaaaatctgc tacaagtcaggagttccccttattgaaaatggaatgattgagcggatgattgagaagctg tttccgtgcgtgatcctcacccccctcgactgcttctgggagggagccaaactccaaggg ggctccgcctacctgcccggccgcccggatatccagtggaccaacctggatccagagcag ctgctggaggagctgggtccctttgcctcccttgagggcttccgggagctgctagacaag gcacaggtgggccaggcctacgtggggcggccctgtctgcaccctgatgacctccactgc ccacctagtgcccccaaccatcacagcaggcaggctcccaatgtggctcacgagctgagt gggggctgccatggcttctcccacaaattcatgcactggcaggaggaattgctgctggga ggcatggccagagacccccaaggagagctgctgagggcagaggccctgcagagcaccttc ttgctgatgagtccccgccagctgtacgagcatttccggggtgactatcagacacatgac attggctggagtgaggagcaggccagcacagtgctacaagcctggcagcggcgctttgtg cagctggcccaggaggccctgcctgagaacgcttcccagcagatccatgccttctcctcc accaccctggatgacatcctgcatgcgttctctgaagtcagtgctgcccgtgtggtggga ggctatctgctcatgctggcctatgcctgtgtgaccatgctgcggtgggactgcgcccag tcccagggttccgtgggccttgccggggtactgctggtggccctggcggtggcctcaggc cttgggctctgtgccctgctcggcatcaccttcaatgctgccactacccaggtgctgccc ttcttggctctgggaatcggcgtggatgacgtattcctgctggcgcatgccttcacagag gctctgcctggcacccctctccaggagcgcatgggcgagtgtctgcagcgcacgggcacc agtgtcgtactcacatccatcaacaacatggccgccttcctcatggctgccctcgttccc atccctgcgctgcgagccttctccctacaggcggccatagtggttggctgcacctttgta gccgtgatgcttgtcttcccagccatcctcagcctggacctacggcggcgccactgccag cgccttgatgtgctctgctgcttctccagtccctgctctgctcaggtgattcagatcctg ccccaggagctgggggacgggacagtaccagtgggcattgcccacctcactgccacagtt caagcctttacccactgtgaagccagcagccagcatgtggtcaccatcctgcctccccaa gcccacctggtgcccccaccttctgacccactgggctctgagctcttcagccctggaggg tccacacgggaccttctaggccaggaggaggagacaaggcagaaggcagcctgcaagtcc ctgccctgtgcccgctggaatcttgcccatttcgcccgctatcagtttgccccgttgctg ctccagtcacatgctaaggccatcgtgctggtgctctttggtgctcttctgggcctgagc ctctacggagccaccttggtgcaagacggcctggccctgacggatgtggtgcctcggggc accaaggagcatgccttcctgagcgcccagctcaggtacttctccctgtacgaggtggcc ctggtgacccagggtggctttgactacgcccactcccaacgcgccctctttgatctgcac cagcgcttcagttccctcaaggcggtgctgcccccaccggccacccaggcaccccgcacc tggctgcactattaccgcaactggctacagggaatccaggctgcctttgaccaggactgg gcttctgggcgcatcacccgccactcgtaccgcaatggctctgaggatggggccctggcc tacaagctgctcatccagactggagacgcccaggagcctctggatttcagccagctgacc acaaggaagctggtggacagagagggactgattccacccgagctcttctacatggggctg accgtgtgggtgagcagtgaccccctgggtctggcagcctcacaggccaacttctacccc ccacctcctgaatggctgcacgacaaatacgacaccacgggggagaaccttcgcatcccg ccagctcagcccttggagtttgcccagttccccttcctgctgcgtggcctccagaagact gcagactttgtggaggccatcgagggggcccgggcagcatgcgcagaggccggccaggct ggggtgcacgcctaccccagcggctcccccttcctcttctgggaacagtatctgggcctg cggcgctgcttcctgctggccgtctgcatcctgctggtgtgcactttcctcgtctgtgct ctgctgctcctcaacccctggacggctggcctcatagtgctggtcctggcgatgatgaca gtggaactctttggtatcatgggtttcctgggcatcaagctgagtgccatccccgtggtg atccttgtggcctctgtaggcattggcgttgagttcacagtccacgtggctctgggcttc ctgaccacccagggcagccggaacctgcgggccgcccatgcccttgagcacacatttgcc cccgtgaccgatggggccatctccacattgctgggtctgctcatgcttgctggttcccac tttgacttcattgtaaggtacttctttgcggcgctgacagtgctcacgctcctgggcctc ctccatggactcgtgctgctgcctgtgctgctgtccatcctgggcccgccgccagaggtg atacagatgtacaaggaaagcccagagatcctgagtccaccagctccacagggaggcggg cttaggcccgaggagatctag |
Protein Sequence |
>8643 : length: 1146 MTRSPPLRELPPSYTPPARTAAPQILAGSLKAPLWLRAYFQGLLFSLGCGIQRHCGKVLF LGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTAR QEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENGMIERMIEKL FPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDPEQLLEELGPFASLEGFRELLDK AQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVAHELSGGCHGFSHKFMHWQEELLLG GMARDPQGELLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASTVLQAWQRRFV QLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAARVVGGYLLMLAYACVTMLRWDCAQ SQGSVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFLLAHAFTE ALPGTPLQERMGECLQRTGTSVVLTSINNMAAFLMAALVPIPALRAFSLQAAIVVGCTFV AVMLVFPAILSLDLRRRHCQRLDVLCCFSSPCSAQVIQILPQELGDGTVPVGIAHLTATV QAFTHCEASSQHVVTILPPQAHLVPPPSDPLGSELFSPGGSTRDLLGQEEETRQKAACKS LPCARWNLAHFARYQFAPLLLQSHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRG TKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRT WLHYYRNWLQGIQAAFDQDWASGRITRHSYRNGSEDGALAYKLLIQTGDAQEPLDFSQLT TRKLVDREGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGENLRIP PAQPLEFAQFPFLLRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGL RRCFLLAVCILLVCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVV ILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSH FDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPPPEVIQMYKESPEILSPPAPQGGG LRPEEI |