Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

8643

Name

PTCH2

Synonymous

PTC2;patched 2;PTCH2;patched 2

Definition

patched homolog 2|protein patched homolog 2

Position

1p34.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

PTCH2(h) --> Ptc2-v1(h) (expression).
Ptc2(h) --> SMOH(m.s.) (regulation of localization)
Ptc2(h) + SMOH(m.s.) <==> Ptc2(h):SMOH(m.s.) (binding)
Ptc2(h) + Ptc1(h) <==> Ptc2(h):Ptc1(h) (binding)
PTCH2(h) --> Ptc2(h) (expression).
SMOH(m.s.) --> Ptc2(h) (increase of promoter activity)
PTCH2(h) --> Ptc2-v2(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

370N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
812N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr1

Promoter: 45080703 - 45082703Agilent_014791

chr1

Promoter: 45080703 - 45082703GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 45080703 - 45082703GSE27584

chr1

Promoter: 45080703 - 45082703Agilent_014791_44K


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