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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 9046 |
Name | DOK2 |
Synonym | p56DOK|p56dok-2;docking protein 2, 56kDa;DOK2;docking protein 2, 56kDa |
Definition | docking protein 2|downstream of tyrosine kinase 2|p56(dok-2) |
Position | 8p21.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 3 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Mutational and expressional analysis of a haploinsufficient tumor suppressor gene DOK2 in gastric and colorectal cancers. |
reviewed | Mutational analysis of DOK2 tumor suppressor gene in acute leukemias. |
potential | Identification of DOK genes as lung tumor suppressors. |
| More detail of all 3 literatures about DOK2 | |
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Pathways and Diseases |
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Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Tie2 Signaling;PID Reactome;500306 |
Disease | Hematological and biochemical traits;NHGRI |
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External Links |
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Links to Entrez Gene | 9046 |
Links to all GeneRIF Items | 9046 |
Links to iHOP | 9046 |
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Sequence Information |
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Nucleotide Sequence |
>9046 : length: 1239 atgggagacggggcagtgaaacaaggcttcttgtatcttcagcagcagcagacgtttgga aagaaatggcgccgcttcggcgcctcactgtatggagggtcggactgcgccttggcccgg ctggagctgcaggagggcccggagaagcctcgtcggtgtgaggctgcccggaaggtcatc cgcctcagtgactgcctgcgggtggccgaggccggcggagaggccagcagcccccgggac accagtgccttcttcctggagaccaaggagcgcctgtacctcctggcggcccctgcagcg gagcgcggcgactgggtgcaggccatctgcctcctggccttccccgggcagaggaaggag ctctcggggccagagggaaagcagagccggccctgcatggaggaaaatgaattgtacagc agcgcagtcacagtcggcccccacaaggaatttgctgtgaccatgagacctacagaagcc agtgagaggtgccacctgcgggggtcctataccctccgggctggggagagtgccctggag ctgtggggtgggcccgagccagggacccagctgtacgactggccctacaggtttctgcgg cgctttgggcgggacaaggtaaccttttcctttgaggcaggccgtcgctgcgtctctgga gagggcaactttgagttcgaaacccggcaaggcaatgagatcttcttggccctggaagag gccatctctgcccagaagaatgctgcacccgctacaccccaaccgcagccagccacaatc cccgcgtcgctgccccggcctgatagcccctactctcggccgcatgactcactgccgccg ccttcacccaccacaccggtgcctgctccacggcctcggggccaggagggggagtatgcc gtgcccttcgatgcggtggcccgttccttggggaagaacttcaggggcatcttggcagtc cctcctcagctcctggccgaccctctgtacgacagcattgaggagaccctgccccctcga cctgaccacatatacgatgagcccgagggagtggctgccctgtccctctatgacagcccg caggagccccggggtgaggcatggaggaggcaggcgacagctgacagggaccctgctggc ctccagcatgtccagccagccgggcaggatttctctgcttctggctggcagccaggaact gagtatgacaatgttgtactaaagaaaggcccaaagtga |
Protein Sequence |
>9046 : length: 412 MGDGAVKQGFLYLQQQQTFGKKWRRFGASLYGGSDCALARLELQEGPEKPRRCEAARKVI RLSDCLRVAEAGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQAICLLAFPGQRKE LSGPEGKQSRPCMEENELYSSAVTVGPHKEFAVTMRPTEASERCHLRGSYTLRAGESALE LWGGPEPGTQLYDWPYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEFETRQGNEIFLALEE AISAQKNAAPATPQPQPATIPASLPRPDSPYSRPHDSLPPPSPTTPVPAPRPRGQEGEYA VPFDAVARSLGKNFRGILAVPPQLLADPLYDSIEETLPPRPDHIYDEPEGVAALSLYDSP QEPRGEAWRRQATADRDPAGLQHVQPAGQDFSASGWQPGTEYDNVVLKKGPK |