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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 11184 |
Name | MAP4K1 |
Synonymous | HPK1;mitogen-activated protein kinase kinase kinase kinase 1;MAP4K1;mitogen-activated protein kinase kinase kinase kinase 1 |
Definition | MAPK/ERK kinase kinase kinase 1|MEK kinase kinase 1|MEKKK 1|hematopoietic progenitor kinase 1 |
Position | 19q13.1-q13.4 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
MAP3K11 | BIOGRID; PUBMED:11053428; |
interacts with |
MAP3K7 | BIOGRID; PUBMED:10224067; |
interacts with |
NCK1 | BIOGRID; PUBMED:11279207; |
interacts with |
NCK1 | BIOGRID; PUBMED:9346925; |
interacts with |
NCK1 | BIOGRID; PUBMED:9891069; |
interacts with |
LAT | BIOGRID; PUBMED:11279207; |
interacts with |
BLNK | BIOGRID; PUBMED:11514608; |
interacts with |
EGFR | BIOGRID; PUBMED:9346925; |
interacts with |
HCLS1 | BIOGRID; PUBMED:10233887; |
interacts with |
GRAP2 | BIOGRID; PUBMED:11313918; |
interacts with |
CRKL | BIOGRID; PUBMED:11279207; |
interacts with |
CRKL | BIOGRID; PUBMED:9788432; |
interacts with |
CRKL | BIOGRID; PUBMED:9891069; |
interacts with |
DBNL | BIOGRID; PUBMED:10567356; |
interacts with |
CRK | BIOGRID; PUBMED:11279207; |
interacts with |
CRK | BIOGRID; PUBMED:9788432; |
interacts with |
CRK | BIOGRID; PUBMED:9891069; |
interacts with |
PPP4C | BIOGRID; PUBMED:15364934; |
interacts with |
MAP3K11 | HPRD; PUBMED:11053428; |
interacts with |
LYN | HPRD; PUBMED:11514608; |
interacts with |
MAP3K7 | HPRD; PUBMED:10224067; |
interacts with |
NCK1 | HPRD; PUBMED:11279207; |
interacts with |
SYK | HPRD; PUBMED:11514608; |
interacts with |
LAT | HPRD; PUBMED:11279207; |
interacts with |
LCP2 | HPRD; PUBMED:11487585; |
interacts with |
BLNK | HPRD; PUBMED:11514608; |
interacts with |
EGFR | HPRD; PUBMED:9346925; |
interacts with |
HCLS1 | HPRD; PUBMED:10233887; |
interacts with |
GRAP2 | HPRD; PUBMED:11313918; |
interacts with |
CASP3 | HPRD; PUBMED:10602493; |
interacts with |
CRKL | HPRD; PUBMED:9891069; |
interacts with |
DBNL | HPRD; PUBMED:10567356; |
interacts with |
CRK | HPRD; PUBMED:11432831; |
interacts with |
DAPP1 | HPRD; PUBMED:14563325; |
interacts with |
SHC1 | HPRD; PUBMED:9346925; |
interacts with |
MAP3K11 | MINT; PUBMED:9346925; |
interacts with |
NCK1 | MINT; PUBMED:17474147; |
interacts with |
NCK1 | MINT; PUBMED:9346925; |
interacts with |
Grap2 | MINT; PUBMED:15100220; |
interacts with |
FYN | MINT; PUBMED:17474147; |
interacts with |
CRK | MINT; PUBMED:17474147; |
interacts with |
ABL1 | MINT; PUBMED:17474147; |
interacts with |
ABL1 | MINT; PUBMED:9346925; |
interacts with |
PLCG1 | MINT; PUBMED:17474147; |
interacts with |
SRC | MINT; PUBMED:17474147; |
interacts with |
PIK3R1 | MINT; PUBMED:17474147; |
Metabolic Interaction | | Top | |
There is no record for MAP4K1 |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
MAP4K1 | IMID; PUBMED:10891492; |
reacts with |
MAP4K1 | IMID; PUBMED:9733512; |
reacts with |
LAMTOR3 | IMID; PUBMED:9733512; |
state change |
RAF1 | IMID; PUBMED:7624324; |
reacts with |
CNKSR1 | IMID; PUBMED:10891492; |
reacts with |
MAP4K1 | NCI_NATURE; PUBMED:10567356; |
reacts with |
MAP4K1 | NCI_NATURE; PUBMED:10903746; |
reacts with |
MAP4K1 | NCI_NATURE; PUBMED:14563325; |
reacts with |
MAP4K1 | NCI_NATURE; PUBMED:9891069; |
state change |
LCK | NCI_NATURE; PUBMED:10903746; |
reacts with |
LCP2 | NCI_NATURE; PUBMED:10567356; |
reacts with |
LCP2 | NCI_NATURE; PUBMED:10903746; |
reacts with |
LCP2 | NCI_NATURE; PUBMED:9891069; |
state change |
CD4 | NCI_NATURE; PUBMED:10903746; |
reacts with |
GRAP2 | NCI_NATURE; PUBMED:10567356; |
reacts with |
GRAP2 | NCI_NATURE; PUBMED:10903746; |
reacts with |
GRAP2 | NCI_NATURE; PUBMED:9891069; |
state change |
HLA-DRA | NCI_NATURE; PUBMED:10903746; |
state change |
CD3E | NCI_NATURE; PUBMED:10903746; |
reacts with |
DBNL | NCI_NATURE; PUBMED:10567356; |
reacts with |
DBNL | NCI_NATURE; PUBMED:9891069; |
reacts with |
DAPP1 | NCI_NATURE; PUBMED:14563325; |
state change |
HLA-DRB1 | NCI_NATURE; PUBMED:10903746; |
state change |
CD3D | NCI_NATURE; PUBMED:10903746; |
state change |
CD247 | NCI_NATURE; PUBMED:10903746; |
state change |
ZAP70 | NCI_NATURE; PUBMED:10903746; |
state change |
CD3G | NCI_NATURE; PUBMED:10903746; |