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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 23365 |
Name | ARHGEF12 |
Synonymous | LARG|PRO2792;Rho guanine nucleotide exchange factor (GEF) 12;ARHGEF12;Rho guanine nucleotide exchange factor (GEF) 12 |
Definition | leukemia-associated RhoGEF|leukemia-associated rho guanine nucleotide exchange factor|rho guanine nucleotide exchange factor 12 |
Position | 11q23.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
TEC | BIOGRID; PUBMED:12515866; |
interacts with |
GNA13 | BIOGRID; PUBMED:11094164; |
interacts with |
GNA12 | BIOGRID; PUBMED:11094164; |
interacts with |
CUL3 | BIOGRID; PUBMED:21670212; |
interacts with |
IGF1R | BIOGRID; PUBMED:11724822; |
interacts with |
RHOA | BIOGRID; PUBMED:11373293; |
interacts with |
RHOA | BIOGRID; PUBMED:12515866; |
interacts with |
PLXNB1 | BIOGRID; PUBMED:12220504; |
interacts with |
PLXNB2 | BIOGRID; PUBMED:12183458; |
interacts with |
LPAR2 | HPRD; PUBMED:15755723; |
interacts with |
CD44 | HPRD; PUBMED:16565089; |
interacts with |
LPAR1 | HPRD; PUBMED:15755723; |
interacts with |
GNA13 | HPRD; PUBMED:12515866; |
interacts with |
IGF1R | HPRD; PUBMED:11724822; |
interacts with |
RHOA | HPRD; PUBMED:11373293; |
interacts with |
ABCA1 | HPRD; PUBMED:16192274; |
interacts with |
PLXNB1 | HPRD; PUBMED:12220504; |
interacts with |
PLXNB2 | HPRD; PUBMED:12183458; |
interacts with |
Lpar1 | MINT; PUBMED:15755723; |
interacts with |
Lpar2 | MINT; PUBMED:15755723; |
interacts with |
IGF1R | MINT; PUBMED:11724822; |
interacts with |
RHOA | MINT; DOI:10.1038/emboj.2010.33; |
Metabolic Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
sequential catalysis |
ARHGEF12 | IMID; PUBMED:11373293; |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
ARHGEF12 | IMID; PUBMED:11724822; |
reacts with |
IGF1R | IMID; PUBMED:11724822; |