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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 2697 |
Name | GJA1 |
Synonymous | AVSD3|CX43|DFNB38|GJAL|HSS|ODDD;gap junction protein, alpha 1, 43kDa;GJA1;gap junction protein, alpha 1, 43kDa |
Definition | connexin 43|connexin-43|gap junction 43 kDa heart protein|gap junction alpha-1 protein |
Position | 6q21-q23.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
MAPK7 | BIOGRID; PUBMED:12637502; |
interacts with |
NEDD4 | BIOGRID; PUBMED:19907029; |
interacts with |
PRKCE | BIOGRID; PUBMED:10679481; |
interacts with |
PRKCA | BIOGRID; PUBMED:11273731; |
interacts with |
HGS | BIOGRID; PUBMED:19808888; |
interacts with |
CAV1 | BIOGRID; PUBMED:11980479; |
interacts with |
GJA5 | BIOGRID; PUBMED:11557558; |
interacts with |
GJA3 | BIOGRID; PUBMED:11739633; |
interacts with |
CSNK1D | BIOGRID; PUBMED:12270943; |
interacts with |
TJP1 | BIOGRID; PUBMED:9707407; |
interacts with |
TSG101 | BIOGRID; PUBMED:19808888; |
interacts with |
S100A1 | BIOGRID; PUBMED:12804600; |
interacts with |
Mapk7 | CELL_MAP; PUBMED:12637502; |
interacts with |
MAPK1 | HPRD; PUBMED:12637502; |
interacts with |
MAPK7 | HPRD; PUBMED:12637502; |
interacts with |
MAPK3 | HPRD; PUBMED:12637502; |
interacts with |
NOV | HPRD; PUBMED:15181016; |
interacts with |
PRKCE | HPRD; PUBMED:10679481; |
interacts with |
PRKCG | HPRD; PUBMED:10871288; |
interacts with |
PRKCA | HPRD; PUBMED:11273731; |
interacts with |
PRKCB | HPRD; PUBMED:10871288; |
interacts with |
CAV1 | HPRD; PUBMED:11980479; |
interacts with |
CSK | HPRD; PUBMED:11035005; |
interacts with |
GJA5 | HPRD; PUBMED:11557558; |
interacts with |
GJC1 | HPRD; PUBMED:11313345; |
interacts with |
GJA3 | HPRD; PUBMED:11739633; |
interacts with |
CSNK1D | HPRD; PUBMED:12270943; |
interacts with |
SRC | HPRD; PUBMED:9278444; |
interacts with |
S100A1 | HPRD; PUBMED:12804600; |
interacts with |
TJP1 | MINT; PUBMED:16944923; |
interacts with |
TJP1 | MINT; PUBMED:9707407; |
interacts with |
SRC | MINT; PUBMED:11035005; |
Metabolic Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
metabolic catalysis |
FOS | NCI_NATURE; PUBMED:12064606;PUBMED:15618352; |
metabolic catalysis |
JUN | NCI_NATURE; PUBMED:12064606;PUBMED:15618352; |
metabolic catalysis |
JUN | NCI_NATURE; PUBMED:15618352;PUBMED:10421804; |
metabolic catalysis |
JUNB | NCI_NATURE; PUBMED:15618352;PUBMED:10421804; |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
state change |
MAPK7 | CELL_MAP; PUBMED:12637502; |
state change |
MAPRE1 | NCI_NATURE; PUBMED:17289573;PUBMED:12640032;PUBMED:15662031; |
state change |
CDH2 | NCI_NATURE; PUBMED:17289573;PUBMED:12640032;PUBMED:15662031; |
state change |
CTNND1 | NCI_NATURE; PUBMED:17289573;PUBMED:12640032;PUBMED:15662031; |
state change |
DCTN1 | NCI_NATURE; PUBMED:17289573;PUBMED:12640032;PUBMED:15662031; |
state change |
CTNNA1 | NCI_NATURE; PUBMED:17289573;PUBMED:12640032;PUBMED:15662031; |
reacts with |
GJA1 | REACTOME; PUBMED:11756680;PUBMED:15033576;PUBMED:1680869;PUBMED:9194487;PUBMED:11964472;PUBMED:11001494;PUBMED:9867835;PUBMED:12149451;PUBMED:12692906;PUBMED:10704454;PUBMED:3999183; |
reacts with |
GJA1 | REACTOME; PUBMED:12149451; |
reacts with |
GJA1 | REACTOME; PUBMED:12506110; |
reacts with |
GJA1 | REACTOME; PUBMED:12907686; |
reacts with |
GJA1 | REACTOME; PUBMED:15855237; |
reacts with |
GJA1 | REACTOME; PUBMED:15998870;PUBMED:11124251; |
reacts with |
GJA1 | REACTOME; PUBMED:17289573;PUBMED:15033576;PUBMED:9841901;PUBMED:12149451; |
reacts with |
GJA1 | REACTOME; PUBMED:17289573;PUBMED:16195341; |
reacts with |
GJA1 | REACTOME; PUBMED:7691412; |
state change |
GJA1 | REACTOME; PUBMED:12506110; |