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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 2697 |
Name | GJA1 |
Synonymous | AVSD3|CX43|DFNB38|GJAL|HSS|ODDD;gap junction protein, alpha 1, 43kDa;GJA1;gap junction protein, alpha 1, 43kDa |
Definition | connexin 43|connexin-43|gap junction 43 kDa heart protein|gap junction alpha-1 protein |
Position | 6q21-q23.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
GJA1(h) --> gja1(h) (expression). | PKCalpha(h) + gja1(h) <==> PKCalpha(h):gja1(h) (binding) | PKCepsilon(h) + gja1(h) <==> PKCepsilon(h):gja1(h) (binding) | gja1(h) + ATP --PKCepsilon(m.s.)--> gja1(h){p} + ADP (phosphorylation) | gja1(h) + ATP --PKCalpha(m.s.)--> gja1(h){p} + ADP (phosphorylation) | zo-1(h) + gja1(h) <==> zo-1(h):gja1(h) (binding) | gja1(h) --> cyclinE(h) (increase of abundance) | GJA1(h) --> gja1(h) (expression). | angiotensin II(m.s.) --> gja1(h) (increase of abundance) |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
262 | Phosphoserine. | Swiss-Prot 53.0 | 306 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 314 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 326 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 328 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 330 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 367 | Phosphoserine (PKC epsilon) | 15534005 | Phospho.ELM 6.0 | 254 | Phosphoserine | 15605363 | Phospho.ELM 6.0 | 261 | Phosphoserine | 15605363 | Phospho.ELM 6.0 | 278 | Phosphoserine | 15605363 | Phospho.ELM 6.0 | 281 | Phosphoserine | 15605363 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
There is no record for GJA1 |