Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

5610

Name

EIF2AK2

Synonymous

EIF2AK1|PKR|PRKR;eukaryotic translation initiation factor 2-alpha kinase 2;EIF2AK2;eukaryotic translation initiation factor 2-alpha kinase 2

Definition

P1/eIF-2A protein kinase|double stranded RNA activated protein kinase|eIF-2A protein kinase 2|interferon-induced, double-stranded RNA-activated protein kinase|interferon-inducible elF2alpha kinase|p68 kinase|protein kinase, interferon-inducible double str

Position

2p22-p21

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 MAP3K5BIOGRID; PUBMED:12473108;

interacts with

 PTGES3BIOGRID; PUBMED:11447118;

interacts with

 HIST2H2ACBIOGRID; PUBMED:9447982;

interacts with

 DNAJC3BIOGRID; PUBMED:8576172;

interacts with

 DNAJC3BIOGRID; PUBMED:9447982;

interacts with

 HSP90AA1BIOGRID; PUBMED:11447118;

interacts with

 FANCCBIOGRID; PUBMED:12397061;

interacts with

 FANCCBIOGRID; PUBMED:15299030;

interacts with

 DBNLBIOGRID; PUBMED:17353931;

interacts with

 IKBKBBIOGRID; PUBMED:10848580;

interacts with

 ILF3BIOGRID; PUBMED:10320367;

interacts with

 ILF3BIOGRID; PUBMED:10400669;

interacts with

 ILF3BIOGRID; PUBMED:11438536;

interacts with

 ILF3BIOGRID; PUBMED:11438540;

interacts with

 EIF2S1BIOGRID; PUBMED:19364808;

interacts with

 CHUKBIOGRID; PUBMED:10848580;

interacts with

 PPP2R5ABIOGRID; PUBMED:10866685;

interacts with

 METAP2BIOGRID; PUBMED:11123929;

interacts with

 ILF2BIOGRID; PUBMED:11438540;

interacts with

 PRKRIP1BIOGRID; PUBMED:12679338;

interacts with

 PRKRABIOGRID; PUBMED:11985496;

interacts with

 PRKRABIOGRID; PUBMED:9687506;

interacts with

 PDGFRBBIOGRID; PUBMED:11350938;

interacts with

 PPP1CABIOGRID; PUBMED:12138106;

interacts with

 STAT3BIOGRID; PUBMED:11350938;

interacts with

 STAT1BIOGRID; PUBMED:11278865;

interacts with

 STAT1BIOGRID; PUBMED:9135145;

interacts with

 TARBP2BIOGRID; PUBMED:11438532;

interacts with

 TARBP2BIOGRID; PUBMED:7568151;

interacts with

 TP53BIOGRID; PUBMED:10348343;

interacts with

 MAP3K5HPRD; PUBMED:12473108;

interacts with

 MAP3K7HPRD; PUBMED:12609980;

interacts with

 TRAF6HPRD; PUBMED:12609980;

interacts with

 TAB2HPRD; PUBMED:12609980;

interacts with

 PTGES3HPRD; PUBMED:11447118;

interacts with

 TLR3HPRD; PUBMED:12609980;

interacts with

 TIRAPHPRD; PUBMED:11526399;

interacts with

 ELF2HPRD; PUBMED:17290288;

interacts with

 HSP90AA1HPRD; PUBMED:11447118;

interacts with

 CASP7HPRD; PUBMED:11555640;

interacts with

 CASP8HPRD; PUBMED:11555640;

interacts with

 CASP3HPRD; PUBMED:11555640;

interacts with

 IKBKBHPRD; PUBMED:10848580;

interacts with

 NFKBIAHPRD; PUBMED:8601309;

interacts with

 ILF3HPRD; PUBMED:11438536;

interacts with

 ILF3HPRD; PUBMED:11438540;

interacts with

 EIF2S1HPRD; PUBMED:8099444;

interacts with

 CHUKHPRD; PUBMED:10648614;

interacts with

 RAC1HPRD; PUBMED:7738010;

interacts with

 JAK1HPRD; PUBMED:17290288;

interacts with

 PPP2R5AHPRD; PUBMED:10866685;

interacts with

 METAP2HPRD; PUBMED:11123929;

interacts with

 ILF2HPRD; PUBMED:11438540;

interacts with

 PRKRIP1HPRD; PUBMED:12679338;

interacts with

 PRKRAHPRD; PUBMED:9687506;

interacts with

 PPP1CCHPRD; PUBMED:12138106;

interacts with

 PDGFRBHPRD; PUBMED:11350938;

interacts with

 PPP1CAHPRD; PUBMED:12138106;

interacts with

 STRBPHPRD; PUBMED:10684936;

interacts with

 STAT3HPRD; PUBMED:11350938;

interacts with

 STAT1HPRD; PUBMED:9135145;

interacts with

 TYK2HPRD; PUBMED:17290288;

interacts with

 TARBP2HPRD; PUBMED:7568151;

interacts with

 PRKRIRHPRD; PUBMED:8576172;

interacts with

 CDC42HPRD; PUBMED:7738010;

interacts with

 CDK1MINT; PUBMED:20395957;

interacts with

 EIF2S1MINT; PUBMED:9431994;

interacts with

 CDC42MINT; PUBMED:7738010;

Metabolic Interaction

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There is no record for EIF2AK2

Signaling Interaction

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Interaction Type

Interactor

Data Source

state change

 PRKRANCI_NATURE; PUBMED:7519779;

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