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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 5933 |
Name | RBL1 |
Synonymous | CP107|PRB1|p107;retinoblastoma-like 1 (p107);RBL1;retinoblastoma-like 1 (p107) |
Definition | 107 kDa retinoblastoma-associated protein|cellular protein 107|retinoblastoma-like protein 1 |
Position | 20q11.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
Interaction Type |
Interactor |
Data Source |
---|---|---|
interacts with |
MCM7 | BIOGRID; PUBMED:9566894; |
interacts with |
TFDP2 | BIOGRID; PUBMED:7739537; |
interacts with |
TFDP1 | BIOGRID; PUBMED:7739537; |
interacts with |
BRF1 | BIOGRID; PUBMED:10330166; |
interacts with |
TAF1 | BIOGRID; PUBMED:9242374; |
interacts with |
MYC | BIOGRID; PUBMED:8076603; |
interacts with |
MYBL2 | BIOGRID; PUBMED:12439743; |
interacts with |
MYBL2 | BIOGRID; PUBMED:12947099; |
interacts with |
KDM5A | BIOGRID; PUBMED:7935440; |
interacts with |
CDK2 | BIOGRID; PUBMED:11884610; |
interacts with |
CDK2 | BIOGRID; PUBMED:9891079; |
interacts with |
ARID4A | BIOGRID; PUBMED:10490602; |
interacts with |
BRCA1 | BIOGRID; PUBMED:11521194; |
interacts with |
BEGAIN | BIOGRID; PUBMED:16189514; |
interacts with |
E2F4 | BIOGRID; PUBMED:12150994; |
interacts with |
E2F4 | BIOGRID; PUBMED:9858615; |
interacts with |
HDAC3 | BIOGRID; PUBMED:10490602; |
interacts with |
HDAC2 | BIOGRID; PUBMED:10490602; |
interacts with |
HDAC1 | BIOGRID; PUBMED:10490602; |
interacts with |
HDAC1 | BIOGRID; PUBMED:9724731; |
interacts with |
EMD | BIOGRID; PUBMED:17620012; |
interacts with |
E2F1 | BIOGRID; PUBMED:8230483; |
interacts with |
E2F5 | BIOGRID; PUBMED:7760804; |
interacts with |
CDKN1C | BIOGRID; PUBMED:12947099; |
interacts with |
CCNA1 | BIOGRID; PUBMED:10022926; |
interacts with |
CREG1 | BIOGRID; PUBMED:9710587; |
interacts with |
RB1 | BIOGRID; PUBMED:10490602; |
interacts with |
RBBP9 | BIOGRID; PUBMED:9697699; |
interacts with |
CCNA2 | BIOGRID; PUBMED:12439743; |
interacts with |
CCNA2 | BIOGRID; PUBMED:8230483; |
interacts with |
CCNA2 | BIOGRID; PUBMED:8798463; |
interacts with |
AATF | BIOGRID; PUBMED:12450794; |
interacts with |
PHB | BIOGRID; PUBMED:10376528; |
interacts with |
CCNE1 | BIOGRID; PUBMED:9891079; |
interacts with |
SMAD4 | BIOGRID; PUBMED:12150994; |
interacts with |
SNW1 | BIOGRID; PUBMED:12466551; |
interacts with |
SUV39H1 | BIOGRID; PUBMED:12588981; |
interacts with |
SUMO3 | BIOGRID; PUBMED:16620772; |
interacts with |
USP4 | BIOGRID; PUBMED:11571651; |
interacts with |
PPP2R3A | BIOGRID; PUBMED:9927208; |
interacts with |
RBBP8 | BIOGRID; PUBMED:16189514; |
interacts with |
RBBP8 | BIOGRID; PUBMED:9721205; |
interacts with |
TFDP1 | CELL_MAP; PUBMED:7958925; |
interacts with |
CDK2 | CELL_MAP; PUBMED:8643455; |
interacts with |
E2F4 | CELL_MAP; PUBMED:7958925; |
interacts with |
E2F4 | CELL_MAP; PUBMED:8643455; |
interacts with |
CCNE1 | CELL_MAP; PUBMED:8643455; |
interacts with |
SMAD4 | CELL_MAP; PUBMED:12150994; |
interacts with |
MYBBP1A | HPRD; PUBMED:17255935; |
interacts with |
TBL3 | HPRD; PUBMED:17255935; |
interacts with |
TFDP1 | HPRD; PUBMED:10082561; |
interacts with |
TFDP1 | HPRD; PUBMED:10540350; |
interacts with |
TFDP1 | HPRD; PUBMED:12150994; |
interacts with |
TFDP1 | HPRD; PUBMED:7958925; |
interacts with |
BRF1 | HPRD; PUBMED:10330166; |
interacts with |
TAF1 | HPRD; PUBMED:9242374; |
interacts with |
NCOR1 | HPRD; PUBMED:17255935; |
interacts with |
NR2E3 | HPRD; PUBMED:17255935; |
interacts with |
MYC | HPRD; PUBMED:8076603; |
interacts with |
MYBL2 | HPRD; PUBMED:12439743; |
interacts with |
KDM5A | HPRD; PUBMED:7935440; |
interacts with |
CDK2 | HPRD; PUBMED:10082561; |
interacts with |
CDK2 | HPRD; PUBMED:11884610; |
interacts with |
CDK2 | HPRD; PUBMED:12096339; |
interacts with |
CDK2 | HPRD; PUBMED:8230483; |
interacts with |
BEGAIN | HPRD; PUBMED:16189514; |
interacts with |
E2F4 | HPRD; PUBMED:10082561; |
interacts with |
E2F4 | HPRD; PUBMED:10540350; |
interacts with |
E2F4 | HPRD; PUBMED:12096339; |
interacts with |
E2F4 | HPRD; PUBMED:12150994; |
interacts with |
E2F4 | HPRD; PUBMED:7958925; |
interacts with |
E2F4 | HPRD; PUBMED:9724731; |
interacts with |
HDAC3 | HPRD; PUBMED:17255935; |
interacts with |
E2F1 | HPRD; PUBMED:9501179; |
interacts with |
E2F5 | HPRD; PUBMED:12150994; |
interacts with |
E2F5 | HPRD; PUBMED:7892279; |
interacts with |
CEBPA | HPRD; PUBMED:10082561; |
interacts with |
CDK9 | HPRD; PUBMED:17255935; |
interacts with |
DHX30 | HPRD; PUBMED:17255935; |
interacts with |
CREG1 | HPRD; PUBMED:9710587; |
interacts with |
DGKZ | HPRD; PUBMED:16286473; |
interacts with |
CDK4 | HPRD; PUBMED:12006580; |
interacts with |
ID2 | HPRD; PUBMED:11034201; |
interacts with |
RB1 | HPRD; PUBMED:1532458; |
interacts with |
RB1 | HPRD; PUBMED:9501179; |
interacts with |
RBBP4 | HPRD; PUBMED:17255935; |
interacts with |
RBBP9 | HPRD; PUBMED:9697699; |
interacts with |
CCNA2 | HPRD; PUBMED:10540350; |
interacts with |
CCNA2 | HPRD; PUBMED:11884610; |
interacts with |
CCNA2 | HPRD; PUBMED:1532458; |
interacts with |
PHB | HPRD; PUBMED:10376528; |
interacts with |
CCNE1 | HPRD; PUBMED:12096339; |
interacts with |
CCNE1 | HPRD; PUBMED:8230483; |
interacts with |
SUV420H2 | HPRD; PUBMED:15750587; |
interacts with |
SMAD4 | HPRD; PUBMED:12150994; |
interacts with |
SNW1 | HPRD; PUBMED:12466551; |
interacts with |
SMAD2 | HPRD; PUBMED:12150994; |
interacts with |
SUV39H1 | HPRD; PUBMED:12588981; |
interacts with |
SP1 | HPRD; PUBMED:7565695; |
interacts with |
USP4 | HPRD; PUBMED:11571651; |
interacts with |
CCND1 | HPRD; PUBMED:8643455; |
interacts with |
SIN3A | HPRD; PUBMED:17255935; |
interacts with |
PPP2R3A | HPRD; PUBMED:9927208; |
interacts with |
RBBP8 | HPRD; PUBMED:9721205; |
interacts with |
NR2E3 | MINT; PUBMED:17255935; |
interacts with |
BEGAIN | MINT; PUBMED:16189514; |
interacts with |
DHX30 | MINT; PUBMED:17255935; |
interacts with |
RBBP7 | MINT; PUBMED:17255935; |
interacts with |
RBBP8 | MINT; PUBMED:16189514; |
Metabolic Interaction | | Top | |
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
TFDP1 | NCI_NATURE; PUBMED:7791762; |
metabolic catalysis |
E2F1 | NCI_NATURE; PUBMED:7791762; |
metabolic catalysis |
RB1 | NCI_NATURE; PUBMED:7791762; |
metabolic catalysis |
RBL1 | NCI_NATURE; PUBMED:7791762; |
metabolic catalysis |
LIN37 | REACTOME; PUBMED:17531812; |
metabolic catalysis |
LIN54 | REACTOME; PUBMED:17531812; |
metabolic catalysis |
LIN52 | REACTOME; PUBMED:17531812; |
metabolic catalysis |
LIN9 | REACTOME; PUBMED:17531812; |
metabolic catalysis |
RBBP4 | REACTOME; PUBMED:17531812; |
metabolic catalysis |
RBL2 | REACTOME; PUBMED:17531812; |
Signaling Interaction | | Top | |
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
TFDP1 | CELL_MAP; PUBMED:12150994; |
reacts with |
E2F4 | CELL_MAP; PUBMED:12150994; |
reacts with |
E2F4 | CELL_MAP; PUBMED:9144196; |
reacts with |
E2F5 | CELL_MAP; PUBMED:12150994; |
reacts with |
E2f5 | CELL_MAP; PUBMED:9144196; |
state change |
CDK4 | CELL_MAP; PUBMED:8643455;PUBMED:12006580; |
reacts with |
RBL1 | CELL_MAP; PUBMED:12150994; |
reacts with |
RBL1 | CELL_MAP; PUBMED:9144196; |
reacts with |
SMAD4 | CELL_MAP; PUBMED:12150994; |
state change |
CCND1 | CELL_MAP; PUBMED:8643455;PUBMED:12006580; |
reacts with |
CDC25A | REACTOME; PUBMED:17531812; |
reacts with |
TOP2A | REACTOME; PUBMED:17531812; |
reacts with |
CDK2 | REACTOME; PUBMED:9199292; |
reacts with |
E2F4 | REACTOME; PUBMED:11884610;PUBMED:7797074;PUBMED:9144196; |
reacts with |
E2F4 | REACTOME; PUBMED:9199292; |
reacts with |
E2F4 | REACTOME; PUBMED:9724731; |
reacts with |
HDAC1 | REACTOME; PUBMED:9724731; |
reacts with |
E2F1 | REACTOME; PUBMED:17531812; |
reacts with |
CDC6 | REACTOME; PUBMED:17531812; |
reacts with |
RBL1 | REACTOME; PUBMED:11884610;PUBMED:7797074;PUBMED:9144196; |
reacts with |
RBL1 | REACTOME; PUBMED:9199292; |
reacts with |
RBL1 | REACTOME; PUBMED:9724731; |
reacts with |
PCNA | REACTOME; PUBMED:17531812; |
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