|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6934 |
Name | TCF7L2 |
Synonymous | TCF-4|TCF4;transcription factor 7-like 2 (T-cell specific, HMG-box);TCF7L2;transcription factor 7-like 2 (T-cell specific, HMG-box) |
Definition | HMG box transcription factor 4|T-cell factor 4|T-cell factor-4 variant A|T-cell factor-4 variant B|T-cell factor-4 variant C|T-cell factor-4 variant D|T-cell factor-4 variant E|T-cell factor-4 variant F|T-cell factor-4 variant G|T-cell factor-4 variant H| |
Position | 10q25.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
NLK | BIOGRID; PUBMED:12556497; |
interacts with |
CTBP1 | BIOGRID; PUBMED:12711682; |
interacts with |
CTNNB1 | BIOGRID; PUBMED:12861022; |
interacts with |
CTNNB1 | BIOGRID; PUBMED:19304756; |
interacts with |
DAZAP2 | BIOGRID; PUBMED:19304756; |
interacts with |
PSEN1 | BIOGRID; PUBMED:11504726; |
interacts with |
JUP | BIOGRID; PUBMED:11711551; |
interacts with |
EP300 | HPRD; PUBMED:12861022; |
interacts with |
CSNK2A1 | HPRD; PUBMED:11711551; |
interacts with |
DAXX | HPRD; PUBMED:16569639; |
interacts with |
CSNK2A2 | HPRD; PUBMED:11711551; |
interacts with |
CTNNB1 | HPRD; PUBMED:11713476; |
interacts with |
CTNNB1 | HPRD; PUBMED:16569639; |
interacts with |
PSEN1 | HPRD; PUBMED:11504726; |
interacts with |
JUP | HPRD; PUBMED:11711551; |
interacts with |
CTNNBIP1 | HPRD; PUBMED:17072306; |
interacts with |
TNIK | MINT; DOI:10.1038/emboj.2009.285; |
interacts with |
Ctnnb1 | MINT; PUBMED:11713475; |
interacts with |
HIC1 | MINT; PUBMED:16724116; |
interacts with |
CTNNB1 | MINT; DOI:10.1038/emboj.2009.285; |
interacts with |
CTNNB1 | MINT; PUBMED:16442529; |
interacts with |
CTNNB1 | MINT; PUBMED:16724116; |
Metabolic Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
metabolic catalysis |
FOS | NCI_NATURE; PUBMED:19521338; |
metabolic catalysis |
JUN | NCI_NATURE; PUBMED:19521338; |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
TLE4 | NCI_NATURE; PUBMED:11266540; |
reacts with |
TLE2 | NCI_NATURE; PUBMED:11266540; |
reacts with |
TNIK | NCI_NATURE; PUBMED:19816403; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:11266540; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:11500377; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:11792709;PUBMED:14638683; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:17146436;PUBMED:16007074; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:18347071; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:19066453; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:19433865;PUBMED:16014379;PUBMED:11080158; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:19503085; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:19816403; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:19901072; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:15060161;PUBMED:17372190; |
reacts with |
TCF7L2 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:17372190; |
state change |
TCF7L2 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:15060161;PUBMED:17372190; |
reacts with |
NCOA2 | NCI_NATURE; PUBMED:11792709;PUBMED:14638683; |
reacts with |
KLF4 | NCI_NATURE; PUBMED:19901072; |
state change |
KLF4 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:15060161;PUBMED:17372190; |
reacts with |
DVL3 | NCI_NATURE; PUBMED:18347071; |
reacts with |
HBP1 | NCI_NATURE; PUBMED:11500377; |
reacts with |
FOS | NCI_NATURE; PUBMED:17146436;PUBMED:16007074; |
reacts with |
BTRC | NCI_NATURE; PUBMED:19066453; |
reacts with |
EP300 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:15060161;PUBMED:17372190; |
reacts with |
CUL1 | NCI_NATURE; PUBMED:19066453; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:11266540; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:11500377; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:11792709;PUBMED:14638683; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:17146436;PUBMED:16007074; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:18347071; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:19066453; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:19433865;PUBMED:16014379;PUBMED:11080158; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:19503085; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:19816403; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:19901072; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:15060161;PUBMED:17372190; |
reacts with |
CTNNB1 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:17372190; |
state change |
CTNNB1 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:15060161;PUBMED:17372190; |
reacts with |
JUN | NCI_NATURE; PUBMED:17146436;PUBMED:16007074; |
reacts with |
JUN | NCI_NATURE; PUBMED:18347071; |
reacts with |
ADCY7 | NCI_NATURE; PUBMED:19901072;PUBMED:15782138;PUBMED:17372190; |
reacts with |
AR | NCI_NATURE; PUBMED:11792709;PUBMED:14638683; |
reacts with |
SKP1 | NCI_NATURE; PUBMED:19066453; |
reacts with |
TRRAP | NCI_NATURE; PUBMED:19066453; |
reacts with |
RUVBL2 | NCI_NATURE; PUBMED:19433865;PUBMED:16014379;PUBMED:11080158; |