Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

7040

Name

TGFB1

Synonymous

CED|DPD1|LAP|TGFB|TGFbeta;transforming growth factor, beta 1;TGFB1;transforming growth factor, beta 1

Definition

TGF-beta 1 protein|TGF-beta-1|latency-associated peptide|transforming growth factor beta-1

Position

19q13.2|19q13.1

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 MMP2BIOGRID; PUBMED:10652271;

interacts with

 MMP9BIOGRID; PUBMED:10652271;

interacts with

 TGFBR2BIOGRID; PUBMED:11157754;

interacts with

 TGFBR3BIOGRID; PUBMED:8106553;

interacts with

 TGFBR1BIOGRID; PUBMED:10716993;

interacts with

 TGFBR1BIOGRID; PUBMED:8235612;

interacts with

 TGFBRAP1BIOGRID; PUBMED:11278302;

interacts with

 TGFB2BIOGRID; PUBMED:11483955;

interacts with

 LTBP1BIOGRID; PUBMED:10930463;

interacts with

 LAMB1BIOGRID; PUBMED:20936779;

interacts with

 EIF3IBIOGRID; PUBMED:9813058;

interacts with

 FNTABIOGRID; PUBMED:8599089;

interacts with

 FKBP1ABIOGRID; PUBMED:11960000;

interacts with

 FMODBIOGRID; PUBMED:8093006;

interacts with

 FCN1BIOGRID; PUBMED:7686157;

interacts with

 ACVRL1BIOGRID; PUBMED:10716993;

interacts with

 YWHAEBIOGRID; PUBMED:11172812;

interacts with

 BGNBIOGRID; PUBMED:8093006;

interacts with

 DCNBIOGRID; PUBMED:7798269;

interacts with

 DCNBIOGRID; PUBMED:8093006;

interacts with

 DCNBIOGRID; PUBMED:9675033;

interacts with

 SMAD2BIOGRID; PUBMED:15009097;

interacts with

 SNIP1BIOGRID; PUBMED:10887155;

interacts with

 THBS1BIOGRID; PUBMED:1550960;

interacts with

 VASNBIOGRID; PUBMED:15247411;

interacts with

 VTNBIOGRID; PUBMED:11796824;

interacts with

 COL2A1BIOGRID; PUBMED:10085302;

interacts with

 TGFBR2CELL_MAP; PUBMED:12729750;PUBMED:11382746;

interacts with

 TGFBR2CELL_MAP; PUBMED:8106553;

interacts with

 Acvrl1CELL_MAP; PUBMED:10716993;

interacts with

 Tgfbr3CELL_MAP; PUBMED:8106553;PUBMED:11278442;

interacts with

 SDC2CELL_MAP; PUBMED:14976204;

interacts with

 MMP14HPRD; PUBMED:11970960;

interacts with

 MMP2HPRD; PUBMED:10652271;

interacts with

 TGFBR2HPRD; PUBMED:7935686;

interacts with

 TGFBR3HPRD; PUBMED:7935686;

interacts with

 TGFB2HPRD; PUBMED:11157754;

interacts with

 LTBP4HPRD; PUBMED:9660815;

interacts with

 BMP2HPRD; PUBMED:11456401;

interacts with

 BMP3HPRD; PUBMED:9434787;

interacts with

 EIF3IHPRD; PUBMED:9813058;

interacts with

 ENGHPRD; PUBMED:12015308;

interacts with

 FNTAHPRD; PUBMED:8599089;

interacts with

 FMODHPRD; PUBMED:8093006;

interacts with

 FCN1HPRD; PUBMED:7686157;

interacts with

 DPTHPRD; PUBMED:9895299;

interacts with

 CTCFHPRD; PUBMED:12099698;

interacts with

 DAXXHPRD; PUBMED:11483955;

interacts with

 CTGFHPRD; PUBMED:10457363;

interacts with

 ITGB6HPRD; PUBMED:10025398;

interacts with

 PZPHPRD; PUBMED:7513640;

interacts with

 ACVRL1HPRD; PUBMED:10716993;

interacts with

 YWHAEHPRD; PUBMED:11172812;

interacts with

 ITGAVHPRD; PUBMED:11970960;

interacts with

 BGNHPRD; PUBMED:10383378;

interacts with

 ITGB8HPRD; PUBMED:11970960;

interacts with

 SMAD4HPRD; PUBMED:12099698;

interacts with

 SPARCHPRD; PUBMED:15034927;

interacts with

 THBS1HPRD; PUBMED:1550960;

interacts with

 VASNHPRD; PUBMED:15247411;

interacts with

 VTNHPRD; PUBMED:11796824;

interacts with

 CCL3HPRD; PUBMED:8568261;

interacts with

 SDC2HPRD; PUBMED:14976204;

interacts with

 COL2A1HPRD; PUBMED:10085302;

interacts with

 TGFBR2INTACT; PUBMED:20856203;

interacts with

 TGFBR3INTACT; PUBMED:20856203;

interacts with

 TGFBR1INTACT; PUBMED:20856203;

interacts with

 LAMB1INTACT; PUBMED:20936779;

interacts with

 ENGINTACT; PUBMED:20856203;

interacts with

 TGFBR2MINT; PUBMED:20860622;

interacts with

 FSTL1MINT; PUBMED:20860622;

interacts with

 DIP2AMINT; PUBMED:20860622;

Metabolic Interaction

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Interaction Type

Interactor

Data Source

metabolic catalysis

 RPS6KB1NCI_NATURE; PUBMED:16611854;

metabolic catalysis

 FOSNCI_NATURE; PUBMED:20141610;PUBMED:2108318;

metabolic catalysis

 JUNNCI_NATURE; PUBMED:20141610;PUBMED:2108318;

Signaling Interaction

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Interaction Type

Interactor

Data Source

reacts with

 TGFBR2NCI_NATURE; PUBMED:10187774;PUBMED:19592636;PUBMED:8756725;PUBMED:14580334;PUBMED:8242742;PUBMED:15702480;

reacts with

 TGFBR2NCI_NATURE; PUBMED:10187774;PUBMED:8756725;PUBMED:8242742;PUBMED:14580334;PUBMED:15702480;

reacts with

 TGFBR2NCI_NATURE; PUBMED:1326540;PUBMED:8294451;PUBMED:9872992;PUBMED:10187774;PUBMED:8242742;

reacts with

 TGFBR2NCI_NATURE; PUBMED:16571110;

reacts with

 TGFBR2NCI_NATURE; PUBMED:18065769;

reacts with

 TGFBR1NCI_NATURE; PUBMED:10187774;PUBMED:19592636;PUBMED:8756725;PUBMED:14580334;PUBMED:8242742;PUBMED:15702480;

reacts with

 TGFBR1NCI_NATURE; PUBMED:10187774;PUBMED:8756725;PUBMED:8242742;PUBMED:14580334;PUBMED:15702480;

reacts with

 TGFBR1NCI_NATURE; PUBMED:16571110;

reacts with

 TGFBR1NCI_NATURE; PUBMED:18065769;

reacts with

 TGFB1NCI_NATURE; PUBMED:10187774;PUBMED:19592636;PUBMED:8756725;PUBMED:14580334;PUBMED:8242742;PUBMED:15702480;

reacts with

 TGFB1NCI_NATURE; PUBMED:10187774;PUBMED:8756725;PUBMED:8242742;PUBMED:14580334;PUBMED:15702480;

reacts with

 TGFB1NCI_NATURE; PUBMED:10639336;PUBMED:14976204;

reacts with

 TGFB1NCI_NATURE; PUBMED:1326540;PUBMED:8294451;PUBMED:9872992;PUBMED:10187774;PUBMED:8242742;

reacts with

 TGFB1NCI_NATURE; PUBMED:16571110;

reacts with

 TGFB1NCI_NATURE; PUBMED:18065769;

reacts with

 CAV1NCI_NATURE; PUBMED:18065769;

reacts with

 FKBP1ANCI_NATURE; PUBMED:10187774;PUBMED:19592636;PUBMED:8756725;PUBMED:14580334;PUBMED:8242742;PUBMED:15702480;

reacts with

 FKBP1ANCI_NATURE; PUBMED:10187774;PUBMED:8756725;PUBMED:8242742;PUBMED:14580334;PUBMED:15702480;

reacts with

 CSNK2BNCI_NATURE; PUBMED:10187774;PUBMED:19592636;PUBMED:8756725;PUBMED:14580334;PUBMED:8242742;PUBMED:15702480;

reacts with

 ACVRL1NCI_NATURE; PUBMED:10187774;PUBMED:19592636;PUBMED:8756725;PUBMED:14580334;PUBMED:8242742;PUBMED:15702480;

reacts with

 ACVRL1NCI_NATURE; PUBMED:10187774;PUBMED:8756725;PUBMED:8242742;PUBMED:14580334;PUBMED:15702480;

reacts with

 ACVRL1NCI_NATURE; PUBMED:16571110;

reacts with

 ACVRL1NCI_NATURE; PUBMED:18065769;

state change

 PLGNCI_NATURE; PUBMED:16554301;PUBMED:2139036;PUBMED:8126064;

reacts with

 PPP1CANCI_NATURE; PUBMED:16571110;

state change

 SMAD7NCI_NATURE; PUBMED:16571110;

reacts with

 SDC2NCI_NATURE; PUBMED:10639336;PUBMED:14976204;

reacts with

 TGFBR2REACTOME; PUBMED:11100470;

reacts with

 TGFBR2REACTOME; PUBMED:1333888;PUBMED:7693660;PUBMED:8242743;

reacts with

 TGFBR2REACTOME; PUBMED:8947046;PUBMED:8047140;

reacts with

 TGFBR2REACTOME; PUBMED:9215638;PUBMED:9335507;

reacts with

 TGFBR2REACTOME; PUBMED:9311995;PUBMED:8980228;PUBMED:9346966;

reacts with

 TGFBR2REACTOME; PUBMED:9865696;

state change

 TGFBR2REACTOME; PUBMED:11100470;

state change

 TGFBR2REACTOME; PUBMED:1333888;PUBMED:7693660;PUBMED:8242743;

state change

 TGFBR2REACTOME; PUBMED:8947046;PUBMED:8047140;

reacts with

 TGFBR1REACTOME; PUBMED:11100470;

reacts with

 TGFBR1REACTOME; PUBMED:1333888;PUBMED:7693660;PUBMED:8242743;

reacts with

 TGFBR1REACTOME; PUBMED:8947046;PUBMED:8047140;

reacts with

 TGFBR1REACTOME; PUBMED:9215638;PUBMED:9335507;

reacts with

 TGFBR1REACTOME; PUBMED:9311995;PUBMED:8980228;PUBMED:9346966;

reacts with

 TGFBR1REACTOME; PUBMED:9865696;

state change

 TGFBR1REACTOME; PUBMED:11100470;

state change

 TGFBR1REACTOME; PUBMED:8947046;PUBMED:8047140;

reacts with

 TGFB1REACTOME; PUBMED:11100470;

reacts with

 TGFB1REACTOME; PUBMED:12482908;PUBMED:15564041;

reacts with

 TGFB1REACTOME; PUBMED:1333888;PUBMED:7693660;PUBMED:8242743;

reacts with

 TGFB1REACTOME; PUBMED:8947046;PUBMED:8047140;

reacts with

 TGFB1REACTOME; PUBMED:9215638;PUBMED:9335507;

reacts with

 TGFB1REACTOME; PUBMED:9311995;PUBMED:8980228;PUBMED:9346966;

reacts with

 TGFB1REACTOME; PUBMED:9865696;

state change

 TGFB1REACTOME; PUBMED:11100470;

state change

 TGFB1REACTOME; PUBMED:1333888;PUBMED:7693660;PUBMED:8242743;

state change

 TGFB1REACTOME; PUBMED:8947046;PUBMED:8047140;

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