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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 7057 |
Name | THBS1 |
Synonymous | THBS|THBS-1|TSP|TSP-1|TSP1;thrombospondin 1;THBS1;thrombospondin 1 |
Definition | thrombospondin-1|thrombospondin-1p180 |
Position | 15q15 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
MMP2 | BIOGRID; PUBMED:10900205; |
interacts with |
MMP9 | BIOGRID; PUBMED:10900205; |
interacts with |
CALCR | BIOGRID; PUBMED:12147682; |
interacts with |
TGFB1 | BIOGRID; PUBMED:1550960; |
interacts with |
F2 | BIOGRID; PUBMED:2435757; |
interacts with |
TFPI | BIOGRID; PUBMED:10922378; |
interacts with |
LRP2 | BIOGRID; PUBMED:7775583; |
interacts with |
LRP1 | BIOGRID; PUBMED:14991768; |
interacts with |
LRP1 | BIOGRID; PUBMED:7775583; |
interacts with |
LRP1 | BIOGRID; PUBMED:9045712; |
interacts with |
DHFR | BIOGRID; PUBMED:10749676; |
interacts with |
FGA | BIOGRID; PUBMED:9867861; |
interacts with |
ELANE | BIOGRID; PUBMED:8463250; |
interacts with |
ITGB3 | BIOGRID; PUBMED:2478219; |
interacts with |
IGFBP5 | BIOGRID; PUBMED:10698186; |
interacts with |
PLG | BIOGRID; PUBMED:2522013; |
interacts with |
PLG | BIOGRID; PUBMED:6438154; |
interacts with |
SCARB2 | BIOGRID; PUBMED:9478926; |
interacts with |
PDGFB | BIOGRID; PUBMED:9334164; |
interacts with |
COL7A1 | BIOGRID; PUBMED:9840442; |
interacts with |
COL4A1 | BIOGRID; PUBMED:3571333; |
interacts with |
COL1A1 | BIOGRID; PUBMED:3571333; |
interacts with |
COL5A1 | BIOGRID; PUBMED:3571333; |
interacts with |
COL2A1 | BIOGRID; PUBMED:3571333; |
interacts with |
COL3A1 | BIOGRID; PUBMED:3571333; |
interacts with |
MMP2 | HPRD; PUBMED:10900205; |
interacts with |
MMP9 | HPRD; PUBMED:10900205; |
interacts with |
TGFB1 | HPRD; PUBMED:1550960; |
interacts with |
TNFRSF11B | HPRD; PUBMED:15799029; |
interacts with |
F2 | HPRD; PUBMED:2435757; |
interacts with |
TFPI | HPRD; PUBMED:10922378; |
interacts with |
LGALS1 | HPRD; PUBMED:12527107; |
interacts with |
LAMB3 | HPRD; PUBMED:9840442; |
interacts with |
LRP5 | HPRD; PUBMED:7775583; |
interacts with |
LRP1 | HPRD; PUBMED:9045712; |
interacts with |
CFH | HPRD; PUBMED:15634279; |
interacts with |
HRG | HPRD; PUBMED:6438154; |
interacts with |
DHFR | HPRD; PUBMED:10749676; |
interacts with |
CTSG | HPRD; PUBMED:8408036; |
interacts with |
FGA | HPRD; PUBMED:9867861; |
interacts with |
ELANE | HPRD; PUBMED:8463250; |
interacts with |
CD36 | HPRD; PUBMED:10772961; |
interacts with |
CALR | HPRD; PUBMED:12147682; |
interacts with |
ITGB3 | HPRD; PUBMED:2478219; |
interacts with |
IGFBP5 | HPRD; PUBMED:10698186; |
interacts with |
ITGA4 | HPRD; PUBMED:11980922; |
interacts with |
ITGA3 | HPRD; PUBMED:11358957; |
interacts with |
ITGAV | HPRD; PUBMED:2478219; |
interacts with |
CD47 | HPRD; PUBMED:9169439; |
interacts with |
PLG | HPRD; PUBMED:2522013; |
interacts with |
ITGB1 | HPRD; PUBMED:11358957; |
interacts with |
ITGB1 | HPRD; PUBMED:11980922; |
interacts with |
SPARC | HPRD; PUBMED:2745554; |
interacts with |
VTN | HPRD; PUBMED:12527107; |
interacts with |
TNFAIP6 | HPRD; PUBMED:16006654; |
interacts with |
SCARB2 | HPRD; PUBMED:9478926; |
interacts with |
SPP1 | HPRD; PUBMED:12527107; |
interacts with |
PDGFB | HPRD; PUBMED:9334164; |
interacts with |
COL7A1 | HPRD; PUBMED:9840442; |
interacts with |
COL1A1 | HPRD; PUBMED:3571333; |
interacts with |
COL2A1 | HPRD; PUBMED:3571333; |
interacts with |
CORO1A | HPRD; PUBMED:10749676; |
interacts with |
COL3A1 | HPRD; PUBMED:3571333; |
interacts with |
SLC25A3 | INTACT; PUBMED:21565611; |
interacts with |
MSR1 | INTACT; PUBMED:21565611; |
interacts with |
LTN1 | INTACT; PUBMED:21565611; |
interacts with |
MAPRE1 | INTACT; PUBMED:21565611; |
interacts with |
MAP1B | INTACT; PUBMED:21565611; |
interacts with |
LOX | INTACT; PUBMED:21565611; |
interacts with |
MAG | INTACT; PUBMED:21565611; |
interacts with |
MDH1 | INTACT; PUBMED:21565611; |
interacts with |
TPI1 | INTACT; PUBMED:21565611; |
interacts with |
TUBA1A | INTACT; PUBMED:21565611; |
interacts with |
TUBB2A | INTACT; PUBMED:21565611; |
interacts with |
TUBB | INTACT; PUBMED:21565611; |
interacts with |
TUBB3 | INTACT; PUBMED:21565611; |
interacts with |
TUBA4B | INTACT; PUBMED:21565611; |
interacts with |
TUBB8 | INTACT; PUBMED:21565611; |
interacts with |
TUBA1C | INTACT; PUBMED:21565611; |
interacts with |
TUBB6 | INTACT; PUBMED:21565611; |
interacts with |
TUBB2C | INTACT; PUBMED:21565611; |
interacts with |
TUBA4A | INTACT; PUBMED:21565611; |
interacts with |
NEFM | INTACT; PUBMED:21565611; |
interacts with |
MYH9 | INTACT; PUBMED:21565611; |
interacts with |
NAP1L1 | INTACT; PUBMED:21565611; |
interacts with |
MYO1C | INTACT; PUBMED:21565611; |
interacts with |
NUP188 | INTACT; PUBMED:21565611; |
interacts with |
NUDT3 | INTACT; PUBMED:21565611; |
interacts with |
GUK1 | INTACT; PUBMED:21565611; |
interacts with |
LDHAL6A | INTACT; PUBMED:21565611; |
interacts with |
CKB | INTACT; PUBMED:21565611; |
interacts with |
CKMT1A | INTACT; PUBMED:21565611; |
interacts with |
CKM | INTACT; PUBMED:21565611; |
interacts with |
PAFAH1B1 | INTACT; PUBMED:21565611; |
interacts with |
ATP1A1 | INTACT; PUBMED:21565611; |
interacts with |
DSG1 | INTACT; PUBMED:21565611; |
interacts with |
BPNT1 | INTACT; PUBMED:21565611; |
interacts with |
BOLA2 | INTACT; PUBMED:21565611; |
interacts with |
ASPH | INTACT; PUBMED:21565611; |
interacts with |
CALM1 | INTACT; PUBMED:21565611; |
interacts with |
CAB39 | INTACT; PUBMED:21565611; |
interacts with |
ATP5A1 | INTACT; PUBMED:21565611; |
interacts with |
DPYSL2 | INTACT; PUBMED:21565611; |
interacts with |
ERC2 | INTACT; PUBMED:21565611; |
interacts with |
ENO3 | INTACT; PUBMED:21565611; |
interacts with |
GRB10 | INTACT; PUBMED:21565611; |
interacts with |
GPC4 | INTACT; PUBMED:21565611; |
interacts with |
HIRIP3 | INTACT; PUBMED:21565611; |
interacts with |
GNAI1 | INTACT; PUBMED:21565611; |
interacts with |
HSPA5 | INTACT; PUBMED:21565611; |
interacts with |
HSP90AA1 | INTACT; PUBMED:21565611; |
interacts with |
HNRNPF | INTACT; PUBMED:21565611; |
interacts with |
DNM1 | INTACT; PUBMED:21565611; |
interacts with |
HSPA8 | INTACT; PUBMED:21565611; |
interacts with |
HSPA9 | INTACT; PUBMED:21565611; |
interacts with |
HRNR | INTACT; PUBMED:21565611; |
interacts with |
DYNLL1 | INTACT; PUBMED:21565611; |
interacts with |
HSPA6 | INTACT; PUBMED:21565611; |
interacts with |
HBA1 | INTACT; PUBMED:21565611; |
interacts with |
GSTM1 | INTACT; PUBMED:21565611; |
interacts with |
HADHA | INTACT; PUBMED:21565611; |
interacts with |
FLG2 | INTACT; PUBMED:21565611; |
interacts with |
FBXO2 | INTACT; PUBMED:21565611; |
interacts with |
FLNC | INTACT; PUBMED:21565611; |
interacts with |
GAS8 | INTACT; PUBMED:21565611; |
interacts with |
EXOC4 | INTACT; PUBMED:21565611; |
interacts with |
GDI2 | INTACT; PUBMED:21565611; |
interacts with |
FH | INTACT; PUBMED:21565611; |
interacts with |
FAR1 | INTACT; PUBMED:21565611; |
interacts with |
GAPDH | INTACT; PUBMED:21565611; |
interacts with |
FSCN1 | INTACT; PUBMED:21565611; |
interacts with |
SIP1 | INTACT; PUBMED:21565611; |
interacts with |
GDI1 | INTACT; PUBMED:21565611; |
interacts with |
FYCO1 | INTACT; PUBMED:21565611; |
interacts with |
GEMIN4 | INTACT; PUBMED:21565611; |
interacts with |
FLNA | INTACT; PUBMED:21565611; |
interacts with |
EXOC1 | INTACT; PUBMED:21565611; |
interacts with |
EEF1A1 | INTACT; PUBMED:21565611; |
interacts with |
DTD1 | INTACT; PUBMED:21565611; |
interacts with |
EMD | INTACT; PUBMED:21565611; |
interacts with |
HADHB | INTACT; PUBMED:21565611; |
interacts with |
ECH1 | INTACT; PUBMED:21565611; |
interacts with |
DCD | INTACT; PUBMED:21565611; |
interacts with |
QDPR | INTACT; PUBMED:21565611; |
interacts with |
CRISPLD2 | INTACT; PUBMED:21565611; |
interacts with |
DNAJA1 | INTACT; PUBMED:21565611; |
interacts with |
DSP | INTACT; PUBMED:21565611; |
interacts with |
DDAH1 | INTACT; PUBMED:21565611; |
interacts with |
CEP290 | INTACT; PUBMED:21565611; |
interacts with |
CDIPT | INTACT; PUBMED:21565611; |
interacts with |
ITGA11 | INTACT; PUBMED:21565611; |
interacts with |
EIF5A | INTACT; PUBMED:21565611; |
interacts with |
IQGAP3 | INTACT; PUBMED:21565611; |
interacts with |
IGHG1 | INTACT; PUBMED:21565611; |
interacts with |
IQCB1 | INTACT; PUBMED:21565611; |
interacts with |
HSPB1 | INTACT; PUBMED:21565611; |
interacts with |
RAB1A | INTACT; PUBMED:21565611; |
interacts with |
MRPL16 | INTACT; PUBMED:21565611; |
interacts with |
RAB3C | INTACT; PUBMED:21565611; |
interacts with |
RNH1 | INTACT; PUBMED:21565611; |
interacts with |
HNRNPA2B1 | INTACT; PUBMED:21565611; |
interacts with |
RAB35 | INTACT; PUBMED:21565611; |
interacts with |
RAB14 | INTACT; PUBMED:21565611; |
interacts with |
TRIM21 | INTACT; PUBMED:21565611; |
interacts with |
RCN2 | INTACT; PUBMED:21565611; |
interacts with |
ALB | INTACT; PUBMED:21565611; |
interacts with |
YWHAB | INTACT; PUBMED:21565611; |
interacts with |
ACTB | INTACT; PUBMED:21565611; |
interacts with |
ALDOA | INTACT; PUBMED:21565611; |
interacts with |
ANXA2 | INTACT; PUBMED:21565611; |
interacts with |
PGD | INTACT; PUBMED:21565611; |
interacts with |
ANGPT2 | INTACT; PUBMED:21565611; |
interacts with |
ANKAR | INTACT; PUBMED:21565611; |
interacts with |
PSMA6 | INTACT; PUBMED:21565611; |
interacts with |
PRKDC | INTACT; PUBMED:21565611; |
interacts with |
PEA15 | INTACT; PUBMED:21565611; |
interacts with |
PSMB2 | INTACT; PUBMED:21565611; |
interacts with |
PSMA7 | INTACT; PUBMED:21565611; |
interacts with |
PSMB6 | INTACT; PUBMED:21565611; |
interacts with |
PRDX1 | INTACT; PUBMED:21565611; |
interacts with |
PSMB5 | INTACT; PUBMED:21565611; |
interacts with |
PFDN2 | INTACT; PUBMED:21565611; |
interacts with |
PGAM1 | INTACT; PUBMED:21565611; |
interacts with |
PSMA2 | INTACT; PUBMED:21565611; |
interacts with |
PSMA4 | INTACT; PUBMED:21565611; |
interacts with |
PGK1 | INTACT; PUBMED:21565611; |
interacts with |
PSMB7 | INTACT; PUBMED:21565611; |
interacts with |
PSMA5 | INTACT; PUBMED:21565611; |
interacts with |
PSMB3 | INTACT; PUBMED:21565611; |
interacts with |
PSMB1 | INTACT; PUBMED:21565611; |
interacts with |
PSMA1 | INTACT; PUBMED:21565611; |
interacts with |
PEBP1 | INTACT; PUBMED:21565611; |
interacts with |
PTPN11 | INTACT; PUBMED:21565611; |
interacts with |
PSMA3 | INTACT; PUBMED:21565611; |
interacts with |
SVOPL | INTACT; PUBMED:21565611; |
interacts with |
SKP1 | INTACT; PUBMED:21565611; |
interacts with |
SYN2 | INTACT; PUBMED:21565611; |
interacts with |
SQRDL | INTACT; PUBMED:21565611; |
interacts with |
SPATA24 | INTACT; PUBMED:21565611; |
interacts with |
SMN1 | INTACT; PUBMED:21565611; |
interacts with |
CALB1 | INTACT; PUBMED:21565611; |
interacts with |
YBX1 | INTACT; PUBMED:21565611; |
interacts with |
XPOT | INTACT; PUBMED:21565611; |
interacts with |
VAMP2 | INTACT; PUBMED:21565611; |
interacts with |
UBE3B | INTACT; PUBMED:21565611; |
interacts with |
ATP6V1G2 | INTACT; PUBMED:21565611; |
interacts with |
UBE2V1 | INTACT; PUBMED:21565611; |
interacts with |
TWF2 | INTACT; PUBMED:21565611; |
interacts with |
UBE2K | INTACT; PUBMED:21565611; |
interacts with |
UCHL1 | INTACT; PUBMED:21565611; |
interacts with |
CALCOCO2 | INTACT; PUBMED:21565611; |
interacts with |
CALU | INTACT; PUBMED:21565611; |
interacts with |
RRBP1 | INTACT; PUBMED:21565611; |
interacts with |
SGPL1 | INTACT; PUBMED:21565611; |
interacts with |
SH3BGRL2 | INTACT; PUBMED:21565611; |
interacts with |
SERPINH1 | INTACT; PUBMED:21565611; |
interacts with |
SEC16A | INTACT; PUBMED:21565611; |
interacts with |
OXCT1 | INTACT; PUBMED:21565611; |
interacts with |
SLC5A3 | INTACT; PUBMED:21565611; |
interacts with |
PPP3R1 | INTACT; PUBMED:21565611; |
interacts with |
LPCAT2 | INTACT; PUBMED:21565611; |
interacts with |
PCP4 | INTACT; PUBMED:21565611; |
interacts with |
PCP4L1 | INTACT; PUBMED:21565611; |
interacts with |
CNTNAP2 | INTACT; PUBMED:21565611; |
interacts with |
CPLX1 | INTACT; PUBMED:21565611; |
Metabolic Interaction | | Top | |
There is no record for THBS1 |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
ITGB3 | NCI_NATURE; PUBMED:12736272;PUBMED:9169439;PUBMED:3875376; |
reacts with |
ITGA4 | NCI_NATURE; PUBMED:11980922; |
reacts with |
ITGA4 | NCI_NATURE; PUBMED:8100842;PUBMED:11980922; |
reacts with |
ITGA3 | NCI_NATURE; PUBMED:10982388;PUBMED:10667601;PUBMED:10446179;PUBMED:11358957; |
reacts with |
ITGA6 | NCI_NATURE; PUBMED:12909644; |
reacts with |
ITGA2B | NCI_NATURE; PUBMED:12736272;PUBMED:9169439;PUBMED:3875376; |
reacts with |
CD47 | NCI_NATURE; PUBMED:12736272;PUBMED:9169439;PUBMED:3875376; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:10982388;PUBMED:10667601;PUBMED:10446179;PUBMED:11358957; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:11980922; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:12909644; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:8100842;PUBMED:11980922; |
reacts with |
THBS1 | NCI_NATURE; PUBMED:10982388;PUBMED:10667601;PUBMED:10446179;PUBMED:11358957; |
reacts with |
THBS1 | NCI_NATURE; PUBMED:11980922; |
reacts with |
THBS1 | NCI_NATURE; PUBMED:12736272;PUBMED:9169439;PUBMED:3875376; |
reacts with |
THBS1 | NCI_NATURE; PUBMED:12909644; |
reacts with |
THBS1 | NCI_NATURE; PUBMED:17879962; |
reacts with |
THBS1 | NCI_NATURE; PUBMED:8100842;PUBMED:11980922; |
reacts with |
VCAM1 | NCI_NATURE; PUBMED:11980922; |
reacts with |
SDC4 | NCI_NATURE; PUBMED:17879962; |
reacts with |
ITGB3 | REACTOME; PUBMED:2010551; |
reacts with |
ITGA4 | REACTOME; PUBMED:15292271;PUBMED:11980922; |
reacts with |
ITGA3 | REACTOME; PUBMED:10982388; |
reacts with |
ITGA2B | REACTOME; PUBMED:2010551; |
reacts with |
ITGB1 | REACTOME; PUBMED:10982388; |
reacts with |
ITGB1 | REACTOME; PUBMED:15292271;PUBMED:11980922; |
reacts with |
THBS1 | REACTOME; PUBMED:10982388; |
reacts with |
THBS1 | REACTOME; PUBMED:15292271;PUBMED:11980922; |
reacts with |
THBS1 | REACTOME; PUBMED:2010551; |