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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 7057 |
Name | THBS1 |
Synonymous | THBS|THBS-1|TSP|TSP-1|TSP1;thrombospondin 1;THBS1;thrombospondin 1 |
Definition | thrombospondin-1|thrombospondin-1p180 |
Position | 15q15 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
LAP(h) + TSP-1(h) <==> LAP(h):TSP-1(h) (binding) | TSP-1(h) + GP4(h) <==> TSP-1(h):GP4(h) (binding) | TSP-1(h) + mmp2(h) <==> TSP-1(h):mmp2(h) (binding) | TSP-1(h) + gelatinase B(h) <==> TSP-1(h):gelatinase B(h) (binding) | TSP-1(h) + mmp2(m) <==> TSP-1(h):mmp2(m) (binding) | Antithrombin-III(m.s.) + thrombin(m.s.) + TSP-1(h) <==> Antithrombin-III(m.s.):thrombin(m.s.):TSP-1(h) (binding) | TSP-1(h) + PDI(h) <==> TSP-1(h):PDI(h) (binding) | TSP-1(h) --> p38(h){p} (increase of phosphorylation) | THBS1(h) --> TSP-1(h) (expression). | IGFBP-5(h) + TSP-1(h) <==> IGFBP-5(h):TSP-1(h) (binding) | TSP-1(h) + IGFBP-3(h) <==> TSP-1(h):IGFBP-3(h) (binding) | TSP-1(h) + IGFBP-4(h) <==> TSP-1(h):IGFBP-4(h) (binding) | THBS1(h) --> TSP-1(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
248 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 360 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 708 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1067 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | P0799 | S | P07996 | OGlycBase6.0 | P0799 | T | P07996 | OGlycBase6.0 | P0799 | T | P07996 | OGlycBase6.0 | P0799 | N | P07996 | OGlycBase6.0 | P0799 | W | P07996 | OGlycBase6.0 | P0799 | W | P07996 | OGlycBase6.0 | P0799 | W | P07996 | OGlycBase6.0 | P0799 | W | P07996 | OGlycBase6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
|---|---|---|
chr15 |
Promoter: 37659072 - 37661072 | Agilent_014791 |
chr15 |
Promoter: 37659072 - 37661072 | GoldenGate_Methylation_Cancer_Panel_I |
chr15 |
Promoter: 37659072 - 37661072 | GSE27584 |
chr15 |
Promoter: 37659072 - 37661072 | Agilent_014791_44K |
chr15 |
Promoter: 37659072 - 37661072 | Agilent_014791 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:14742272 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:14507661 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:11146446 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:16075282 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:17374440 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:11306456 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12695555 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12746473 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12759541 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12579314 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:16983315 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:14654541 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:15365725 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:15892004 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12826052 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:16391867 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:15122305 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:15389252 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:16336454 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:15623630 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:15788647 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:14559817 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12660028 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:16858686 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:15172987 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:17139617 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:10766168 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12213730 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12114423 |
chr15 |
Promoter: 37659072 - 37661072 | PMID:12632081 |