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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 7248 |
Name | TSC1 |
Synonymous | LAM|TSC;tuberous sclerosis 1;TSC1;tuberous sclerosis 1 |
Definition | hamartin|tuberous sclerosis 1 protein|tumor suppressor |
Position | 9q34 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
MSN | BIOGRID; PUBMED:12226091; |
interacts with |
TBC1D7 | BIOGRID; PUBMED:17658474; |
interacts with |
CDK1 | BIOGRID; PUBMED:14551205; |
interacts with |
NEFL | BIOGRID; PUBMED:12226091; |
interacts with |
RPS6KA1 | BIOGRID; PUBMED:15342917; |
interacts with |
BECN1 | BIOGRID; PUBMED:20562859; |
interacts with |
AXIN1 | BIOGRID; PUBMED:12511557; |
interacts with |
EZR | BIOGRID; PUBMED:10806479; |
interacts with |
GSK3B | BIOGRID; PUBMED:12511557; |
interacts with |
FBXW5 | BIOGRID; PUBMED:18381890; |
interacts with |
PTK2 | BIOGRID; PUBMED:17043358; |
interacts with |
CDKN1B | BIOGRID; PUBMED:15355997; |
interacts with |
DOCK7 | BIOGRID; PUBMED:15963462; |
interacts with |
RHEB | BIOGRID; PUBMED:12820960; |
interacts with |
YWHAB | BIOGRID; PUBMED:12176984; |
interacts with |
YWHAZ | BIOGRID; PUBMED:12176984; |
interacts with |
PAM | BIOGRID; PUBMED:14559897; |
interacts with |
ACTA1 | BIOGRID; PUBMED:10806479; |
interacts with |
AKT1 | BIOGRID; PUBMED:12167664; |
interacts with |
AKT1 | BIOGRID; PUBMED:15342917; |
interacts with |
PLK1 | BIOGRID; PUBMED:16339216; |
interacts with |
TSC2 | BIOGRID; PUBMED:10807585; |
interacts with |
TSC2 | BIOGRID; PUBMED:10915759; |
interacts with |
TSC2 | BIOGRID; PUBMED:11175345; |
interacts with |
TSC2 | BIOGRID; PUBMED:11290735; |
interacts with |
TSC2 | BIOGRID; PUBMED:11741832; |
interacts with |
TSC2 | BIOGRID; PUBMED:11741833; |
interacts with |
TSC2 | BIOGRID; PUBMED:12167664; |
interacts with |
TSC2 | BIOGRID; PUBMED:12176984; |
interacts with |
TSC2 | BIOGRID; PUBMED:12511557; |
interacts with |
TSC2 | BIOGRID; PUBMED:14551205; |
interacts with |
TSC2 | BIOGRID; PUBMED:14651849; |
interacts with |
TSC2 | BIOGRID; PUBMED:15340059; |
interacts with |
TSC2 | BIOGRID; PUBMED:15851026; |
interacts with |
TSC2 | BIOGRID; PUBMED:15963462; |
interacts with |
TSC2 | BIOGRID; PUBMED:16339216; |
interacts with |
TSC2 | BIOGRID; PUBMED:16424383; |
interacts with |
TSC2 | BIOGRID; PUBMED:16636147; |
interacts with |
TSC2 | BIOGRID; PUBMED:17077083; |
interacts with |
TSC2 | BIOGRID; PUBMED:17658474; |
interacts with |
TSC2 | BIOGRID; PUBMED:9580671; |
interacts with |
Tsc2 | BIOGRID; PUBMED:12147258; |
interacts with |
DAPK1 | MINT; PUBMED:21134130; |
interacts with |
YWHAG | MINT; PUBMED:15324660; |
interacts with |
YWHAB | MINT; PUBMED:15324660; |
interacts with |
TSC2 | MINT; PUBMED:20412061; |
interacts with |
TSC2 | MINT; PUBMED:21134130; |
interacts with |
TSC2 | MINT; PUBMED:9580671; |
Metabolic Interaction | | Top | |
There is no record for TSC1 |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
state change |
RPS6KA1 | NCI_NATURE; PUBMED:15342917; |
state change |
GSK3B | NCI_NATURE; PUBMED:16959574; |
reacts with |
DDIT4 | NCI_NATURE; PUBMED:15545625;PUBMED:18198340; |
reacts with |
IKBKB | NCI_NATURE; PUBMED:17693255; |
state change |
AKT1 | NCI_NATURE; PUBMED:12820960;PUBMED:12172553;PUBMED:17386266; |
reacts with |
TSC2 | NCI_NATURE; PUBMED:12820960;PUBMED:12172553;PUBMED:17386266; |
reacts with |
TSC2 | NCI_NATURE; PUBMED:14651849; |
reacts with |
TSC2 | NCI_NATURE; PUBMED:15342917; |
reacts with |
TSC2 | NCI_NATURE; PUBMED:15545625;PUBMED:18198340; |
reacts with |
TSC2 | NCI_NATURE; PUBMED:15851026; |
reacts with |
TSC2 | NCI_NATURE; PUBMED:16959574; |
reacts with |
TSC2 | NCI_NATURE; PUBMED:17693255; |
reacts with |
TSC1 | NCI_NATURE; PUBMED:12820960;PUBMED:12172553;PUBMED:17386266; |
reacts with |
TSC1 | NCI_NATURE; PUBMED:14651849; |
reacts with |
TSC1 | NCI_NATURE; PUBMED:15342917; |
reacts with |
TSC1 | NCI_NATURE; PUBMED:15545625;PUBMED:18198340; |
reacts with |
TSC1 | NCI_NATURE; PUBMED:15851026; |
reacts with |
TSC1 | NCI_NATURE; PUBMED:16959574; |
reacts with |
TSC1 | NCI_NATURE; PUBMED:17693255; |
reacts with |
TSC1 | REACTOME; PUBMED:14651849; |
reacts with |
TSC1 | REACTOME; PUBMED:15314020; |