Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

9636

Name

ISG15

Synonymous

G1P2|IFI15|IP17|UCRP|hUCRP;ISG15 ubiquitin-like modifier;ISG15;ISG15 ubiquitin-like modifier

Definition

interferon, alpha-inducible protein (clone IFI-15K)|interferon-induced 15 kDa protein|interferon-induced 17 kDa protein|interferon-induced 17-kDa/15-kDa protein|interferon-stimulated protein, 15 kDa|ubiquitin cross-reactive protein|ubiquitin-like protein

Position

1p36.33

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 NEDD4BIOGRID; PUBMED:18287095;

interacts with

 ERCC2BIOGRID; PUBMED:16884686;

interacts with

 HSPA4BIOGRID; PUBMED:16884686;

interacts with

 ENO1BIOGRID; PUBMED:16884686;

interacts with

 FUT4BIOGRID; PUBMED:16884686;

interacts with

 ELF3BIOGRID; PUBMED:17353931;

interacts with

 DDX58BIOGRID; PUBMED:17719635;

interacts with

 RGS3BIOGRID; PUBMED:16884686;

interacts with

 PPM1BBIOGRID; PUBMED:16884686;

interacts with

 STK38BIOGRID; PUBMED:16884686;

interacts with

 UBE2D3BIOGRID; PUBMED:17719635;

interacts with

 USP18BIOGRID; PUBMED:16189514;

interacts with

 TRIM25BIOGRID; PUBMED:17069755;

interacts with

 UBA7BIOGRID; PUBMED:16189514;

interacts with

 UBA7BIOGRID; PUBMED:16884686;

interacts with

 SEPT2BIOGRID; PUBMED:18305167;

interacts with

 IFNB1HPRD; PUBMED:16872604;

interacts with

 UBE2E2HPRD; PUBMED:16872604;

interacts with

 USP18HPRD; PUBMED:16189514;

interacts with

 UBA7HPRD; PUBMED:14976209;

interacts with

 UBA7HPRD; PUBMED:16872604;

interacts with

 FLNBMINT; DOI:10.1038/embor.2009.23;

interacts with

 PPM1BMINT; PUBMED:16872604;

interacts with

 USP18MINT; PUBMED:16189514;

interacts with

 UBA7MINT; PUBMED:16189514;

Metabolic Interaction

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Interaction Type

Interactor

Data Source

metabolic catalysis

 IRF9REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

metabolic catalysis

 STAT2REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

Signaling Interaction

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Interaction Type

Interactor

Data Source

reacts with

 ADARREACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 HERC5REACTOME; PUBMED:18057259;

reacts with

 GBP2REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 EGR1REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 DDX58REACTOME; PUBMED:18057259;

reacts with

 IFI6REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFIT1REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 ISG15REACTOME; PUBMED:18057259;

reacts with

 RNASELREACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFITM2REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFIT3REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFITM3REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFI35REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 ISG20REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IP6K2REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFI27REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFITM1REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 IFIT2REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 PSMB8REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

reacts with

 XAF1REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454;

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