|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 545 |
Name | ATR |
Synonymous | FRP1|MEC1|SCKL|SCKL1;ataxia telangiectasia and Rad3 related;ATR;ataxia telangiectasia and Rad3 related |
Definition | FRAP-related protein 1|FRAP-related protein-1|MEC1, mitosis entry checkpoint 1, homolog|Rad3 related protein|ataxia telangiectasia and Rad3-related protein|protein kinase ATR|serine/threonine-protein kinase ATR |
Position | 3q22-q24 |
Gene Type | protein-coding |
Gene Mutation: | Substitution Insertion & Deletion Other Mutation |
Substitution | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Substitution - coding silent; c.6192C>T; 3:143686701-143686701 |
y; skin | malignant_melanoma |
Substitution - coding silent; c.387A>G; 3:143764547-143764547 |
stomach | adenocarcinoma; carcinoma |
Substitution - coding silent; c.6192C>T; 3:143686701-143686701 |
y; skin | malignant_melanoma |
Substitution - coding silent; c.5868C>T; 3:143697923-143697923 |
y; breast | ductal_carcinoma; carcinoma |
Substitution - coding silent; c.1776T>A; |
y; stomach | adenocarcinoma; carcinoma |
Substitution - coding silent; c.2070G>A; |
y; upper_aerodigestive_tract; pharynx; oropharynx | squamous_cell_carcinoma; carcinoma |
Substitution - coding silent; c.5868C>T; 3:143697923-143697923 |
y; breast | ductal_carcinoma; carcinoma |
Substitution - coding silent; c.6192C>T; 3:143686701-143686701 |
y; skin | malignant_melanoma |
Indel | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Deletion - Frameshift; c.6279_6280delAT; |
y; liver | hepatocellular_carcinoma; carcinoma |
Deletion - Frameshift; c.3790_3796delATAAAAG; 3:143737663-143737669 |
ovary | serous_carcinoma; carcinoma |
Other Mutation | | Top | |
There is no record for ATR |