Basic Information
Gene ID	545
Name	ATR
Synonymous	FRP1\|MEC1\|SCKL\|SCKL1;ataxia telangiectasia and Rad3 related;ATR;ataxia telangiectasia and Rad3 related
Definition	FRAP-related protein 1\|FRAP-related protein-1\|MEC1, mitosis entry checkpoint 1, homolog\|Rad3 related protein\|ataxia telangiectasia and Rad3-related protein\|protein kinase ATR\|serine/threonine-protein kinase ATR
Position	3q22-q24
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database
p300(h) + ATR(h) <==> p300(h):ATR(h) (binding)
ATR(h) --> ATM(h){pS1981} (increase of phosphorylation)
ATR(h) + brca1(h) <==> ATR(h):brca1(h) (binding)
ATR(h) + ATP --> ATR(h){p} + ADP (phosphorylation)
ATR(h) + TIF2(h) <==> ATR(h):TIF2(h) (binding)
ATR(h) --> ATR(h) (expression).
Chk1(h) + ATP --ATR(h)--> Chk1(h){p} + ADP (phosphorylation)
p53(h) + ATP --ATR(h)--> p53(h){pS15} + ADP (phosphorylation)
PML-X(h) + ATP --ATR(h)--> ADP + PML(h){p} (phosphorylation)
Bid(m) + 2 ATP --ATR(h)--> Bid(m){pS61}{pS78} + 2 ADP (phosphorylation)
Chk1(h) + ATP --ATR(h)--> Chk1(h){pS345} + ADP (phosphorylation)
brca1(h) + ATP --ATR(h)--> brca1(h){p} + ADP (phosphorylation)
ATR(h) + ATP --ATR(m.s.)--> ATR(h){pS1333} + ADP (phosphorylation; automodification)
ATR(h) --> ATR(h) (expression).

Location (AA)	PTM type	Literature	Database
1989	Phosphothreonine	15302935	Phospho.ELM 6.0