|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 54790 |
Name | TET2 |
Synonymous | KIAA1546|MDS;tet methylcytosine dioxygenase 2;TET2;tet methylcytosine dioxygenase 2 |
Definition | methylcytosine dioxygenase TET2|probable methylcytosine dioxygenase TET2|tet oncogene family member 2 |
Position | 4q24 |
Gene Type | protein-coding |
Gene Mutation: | Substitution Insertion & Deletion Other Mutation |
Substitution | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Substitution - coding silent; c.459T>G; |
pancreas | NS |
Substitution - coding silent; c.3186C>T; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Indel | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Deletion - Frameshift; c.822_822delC; |
haematopoietic_and_lymphoid_ti | myeloproliferative_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.937_940delACCT; |
haematopoietic_and_lymphoid_ti | blast_phase_essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4664_4665delAG; |
haematopoietic_and_lymphoid_ti | myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.2570_2570delA; |
haematopoietic_and_lymphoid_ti | post-thrombocythaemic-polycythaemic; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.5647_5647delA; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.3411_3411delG; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.?del?; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.4071_4071delG; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.4589_4599del11; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.4258_4261delTTAT; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5647_5647delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?delA; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.5645_5646delCC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.945_945delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3729_3729delA; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5338_5338delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1602_1605delAAAC; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1602_1605delAAAC; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1336_1337delTT; |
haematopoietic_and_lymphoid_ti | blastic_plasmacytoid_dentritic_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.2742_2742delT; |
haematopoietic_and_lymphoid_ti; lymph_node | peripheral_T_cell_lymphoma_unspecified; lymphoid_neoplasm |
Deletion - Frameshift; c.945_945delC; |
haematopoietic_and_lymphoid_ti; lymph_node | peripheral_T_cell_lymphoma_unspecified; lymphoid_neoplasm |
Deletion - Frameshift; c.651_651delC; |
haematopoietic_and_lymphoid_ti | peripheral_T_cell_lymphoma_unspecified; lymphoid_neoplasm |
Deletion - Frameshift; c.2282_2282delC; |
haematopoietic_and_lymphoid_ti | peripheral_T_cell_lymphoma_unspecified; lymphoid_neoplasm |
Deletion - Frameshift; c.783_783delC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.2818_2818delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4010_4025del16; |
haematopoietic_and_lymphoid_ti | essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4319_4319delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia_associated_with_MDS; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.3112_3121del10; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.2306_2306delA; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.(3893_3897)delG; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4502_4505delAAAC; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.521_521delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1842_1842delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2305_2305delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2450_2454delCCCCT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - In frame; c.5665_5670delCCCAAT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5111_5123del13; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3861_3861delT; |
haematopoietic_and_lymphoid_ti | M1; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2355_2355delT; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.5704_5704delT; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.2271_2277delCCAGACT; |
haematopoietic_and_lymphoid_ti; lymph_node | peripheral_T_cell_lymphoma_unspecified; lymphoid_neoplasm |
Deletion - Frameshift; c.4723_4745del23; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.1471_1471delC; |
haematopoietic_and_lymphoid_ti | post-thrombocythaemic-polycythaemic; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.1716_1716delT; |
haematopoietic_and_lymphoid_ti | splanchnic_vein_thrombosis; other |
Deletion - Frameshift; c.1955_1955delA; |
haematopoietic_and_lymphoid_ti | blast_phase_essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4999_5014del16; |
haematopoietic_and_lymphoid_ti | primary; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.1974_1975delCC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_ringed_sideroblasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - In frame; c.?; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.3269_3269delA; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - In frame; c.3708_3716del9; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.822_822delC; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.3487_3487delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5163_5163delG; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.(5187_5190)del1; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3138_3138delT; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.998_998delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3732_3733delCT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3957_3957delA; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2176_2179delCAGG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4317_4317delA; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3456_3456delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4317_4318delAC; |
haematopoietic_and_lymphoid_ti | M1; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4258_4264delTTATACA; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1799_1799delT; |
haematopoietic_and_lymphoid_ti | M1; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3813_3813delC; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2246_2249delAAAT; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.651_651delC; |
haematopoietic_and_lymphoid_ti | blastic_plasmacytoid_dentritic_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.2896_2897delCA; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.783_783delC; |
haematopoietic_and_lymphoid_ti | myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.783_783delC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.5036_5036delA; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.5381_5385delCTAAT; |
haematopoietic_and_lymphoid_ti | essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1825_1825delT; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2540_2543delAGAC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2477_2477delG; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2133_2133delG; |
haematopoietic_and_lymphoid_ti | refractory_cytopenia_with_multilinear_dysplasia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.1378_1378delT; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.3048_3048delT; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.3970_3971delTC; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1118_1122delAAAAT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1219_1219delT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2149_2150delCA; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.980_980delC; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2003_2003delT; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4258_4264delTTATACA; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2147_2147delC; |
haematopoietic_and_lymphoid_ti | M1; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5209_5210delAC; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5486_5486delC; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2982_2982delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia_associated_with_MDS; haematopoietic_neoplasm |
Deletion - Frameshift; c.1342_1342delG; |
haematopoietic_and_lymphoid_ti; lymph_node | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1033_1036delAAGC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.3667_3667delG; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1645_1645delA; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1664_1664delC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1925_1925delA; |
haematopoietic_and_lymphoid_ti | splanchnic_vein_thrombosis; other |
Deletion - Frameshift; c.5695_5695delC; |
haematopoietic_and_lymphoid_ti | post-thrombocythaemic-polycythaemic; myelofibrosis; haematopoietic_neoplasm |
Deletion - In frame; c.?_?del?; |
haematopoietic_and_lymphoid_ti | essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2133_2133delG; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_ringed_sideroblasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.1720_1720delC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.1973_1974delAC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_ringed_sideroblasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2570_2570delA; |
haematopoietic_and_lymphoid_ti | post-thrombocythaemic-polycythaemic; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.4266_4266delA; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.3487_3487delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1795_1798delCAAA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4474_4474delG; |
haematopoietic_and_lymphoid_ti | blast_phase_chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1378_1378delT; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.1851_1851delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2003_2003delT; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.783_783delC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.4062delA; |
haematopoietic_and_lymphoid_ti | primary; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.5570_5580del11; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del?; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.971_971delA; |
haematopoietic_and_lymphoid_ti | post-thrombocythaemic-polycythaemic; myelofibrosis; haematopoietic_neoplasm |
Deletion - In frame; c.?; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2570_2570delA; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - In frame; c.?; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.5456_5456delT; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.490_491delAC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.630_631delTG; |
haematopoietic_and_lymphoid_ti | essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1386_1386delT; |
haematopoietic_and_lymphoid_ti | B_cell_lymphoma_unspecified; lymphoid_neoplasm |
Deletion - Frameshift; c.3417_3417delT; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2441_2441delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3448_3448delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4705_4706delTA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2447_2447delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3205_3205delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5192_5192delG; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4113_4120delCACTGCAT; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3443_3443delA; |
haematopoietic_and_lymphoid_ti | myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.3088_3088delC; |
haematopoietic_and_lymphoid_ti | blastic_plasmacytoid_dentritic_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.865_865delG; |
haematopoietic_and_lymphoid_ti | blastic_plasmacytoid_dentritic_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.783_783delC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.4_4delG; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3309_3310delTT; |
haematopoietic_and_lymphoid_ti | primary; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.4283_4283delA; |
haematopoietic_and_lymphoid_ti | primary; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.3778_3778delA; |
haematopoietic_and_lymphoid_ti | essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4440_4440delC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_ringed_sideroblasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.3138_3138delT; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.3658_3658delA; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.4271_4271delC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2999_2999delA; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4576_4576delC; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Deletion - Frameshift; c.5950_5957delGTAACTAC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3921_3921delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5283_5283delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4865_4865delT; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.368_368delG; |
haematopoietic_and_lymphoid_ti | M1; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1020_1020delC; |
haematopoietic_and_lymphoid_ti | refractory_cytopenia_with_multilinear_dysplasia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.1557_1557delT; |
haematopoietic_and_lymphoid_ti | blast_phase_chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.651_651delC; |
haematopoietic_and_lymphoid_ti | blast_phase_chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.783_783delC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.783_783delC; |
haematopoietic_and_lymphoid_ti; lymph_node | angioimmunoblastic_T_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1887_1887delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5060_5061delAG; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.942_945delTTCC; |
haematopoietic_and_lymphoid_ti | primary; myelofibrosis; haematopoietic_neoplasm |
Deletion - Frameshift; c.3623_3623delA; |
haematopoietic_and_lymphoid_ti | refractory_cytopenia_with_multilinear_dysplasia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2570_2570delA; |
haematopoietic_and_lymphoid_ti | blast_phase_myeloproliferative_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.4723_4745del23; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.5844_5844delA; |
haematopoietic_and_lymphoid_ti; lymph_node | acute_lymphoblastic_B_cell_leukaemia; lymphoid_neoplasm |
Deletion - Frameshift; c.4478_4478delA; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.1823_1823delA; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.3508_3508delC; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.5647_5647delA; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.1354_1354delG; |
haematopoietic_and_lymphoid_ti | systemic_mastocytosis; mast_cell_neoplasm; haematopoietic_neoplasm |
Deletion - Frameshift; c.3312_3312delT; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5564_5573del10; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3344_3344delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.519_519delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.688_689delCT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1753_1753delT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3528_3528delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2497_2497delT; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.4148_4148delG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5128_5131delACCA; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.3885_3885delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5374_5374delC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.5041_5048delCCAAGGTT; |
haematopoietic_and_lymphoid_ti | Ph_negative-bcr_negative; chronic_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.2282_2282delC; |
haematopoietic_and_lymphoid_ti | M5; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.?_?del10; |
haematopoietic_and_lymphoid_ti | essential_thrombocythaemia; haematopoietic_neoplasm |
Deletion - Frameshift; c.1802_1802delC; |
haematopoietic_and_lymphoid_ti | myelodysplastic_syndrome; haematopoietic_neoplasm |
Deletion - Frameshift; c.2001_2001delT; |
haematopoietic_and_lymphoid_ti | myelodysplastic_syndrome; haematopoietic_neoplasm |
Other Mutation | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | post-thrombocythaemic-polycythaemic; myelofibrosis; haematopoietic_neoplasm |
Whole gene deletion; c.?; |
haematopoietic_and_lymphoid_ti | chronic_myelomonocytic_leukaemia; haematopoietic_neoplasm |
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | refractory_anaemia; myelodysplastic_syndrome; haematopoietic_neoplasm |
Whole gene deletion; c.?; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | polycythaemia_vera; haematopoietic_neoplasm |
Complex - frameshift; c.2000_2016>C; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - frameshift; c.1137_1138TT>C; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - frameshift; c.3237_3237A>CCC; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - frameshift; c.3489_3498CATGGAAGAA>TAAGGT; |
haematopoietic_and_lymphoid_ti | M2; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |
Complex - frameshift; c.5539_5541TGG>A; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Whole gene deletion; c.1_6009del6009; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - deletion inframe; c.4005_4009AACAT>TG; |
haematopoietic_and_lymphoid_ti | acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - frameshift; c.4260_4264ATACA>GTC; |
haematopoietic_and_lymphoid_ti | M5; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - frameshift; c.4634_4635AG>C; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - frameshift; c.2638_2641CACA>AC; |
haematopoietic_and_lymphoid_ti | M4; acute_myeloid_leukaemia; haematopoietic_neoplasm |
Complex - frameshift; c.1090_1091GG>T; |
haematopoietic_and_lymphoid_ti | myelodysplastic_syndrome; haematopoietic_neoplasm |
Complex - frameshift; c.1909_1911GAA>AT; |
haematopoietic_and_lymphoid_ti | refractory_anaemia_with_excess_blasts; myelodysplastic_syndrome; haematopoietic_neoplasm |