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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 639 |
Name | PRDM1 |
Synonymous | BLIMP1|PRDI-BF1;PR domain containing 1, with ZNF domain;PRDM1;PR domain containing 1, with ZNF domain |
Definition | B-lymphocyte-induced maturation protein 1|BLIMP-1|PR domain zinc finger protein 1|PRDI-binding factor-1|beta-interferon gene positive-regulatory domain I binding factor |
Position | 6q21 |
Gene Type | protein-coding |
Gene Mutation: | Substitution Insertion & Deletion Other Mutation |
Substitution | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Substitution - coding silent; c.2170C>T; |
y; skin; upper_back | malignant_melanoma |
Indel | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Deletion - Frameshift; c.124_127delCAGG; 6:106642958-106642961 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.733_734delGA; 6:106659569-106659570 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1810_1819del10; 6:106661494-106661503 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.125_128delAGGC; 6:106642959-106642962 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.632_633delAG; 6:106659468-106659469 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.37_38delTG; 6:106642871-106642872 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.733_734delGA; 6:106659569-106659570 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.357_358delAA; 6:106653921-106653922 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.632_633delAG; 6:106659468-106659469 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.76_95del20; 6:106642910-106642929 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.733_734delGA; 6:106659569-106659570 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.594_595delGA; 6:106659430-106659431 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.557_567del11; 6:106659393-106659403 |
haematopoietic_and_lymphoid_ti | lymphoid_neoplasm |
Other Mutation | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Complex - frameshift; c.111_111C>GG; 6:106642945-106642945 |
haematopoietic_and_lymphoid_ti; central_nervous_system | primary_central_nervous_system_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2370del2370; |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2370del2370; |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2370del2370; |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |