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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6416 |
Name | MAP2K4 |
Synonymous | JNKK|JNKK1|MAPKK4|MEK4|MKK4|PRKMK4|SAPKK-1|SAPKK1|SEK1|SERK1;mitogen-activated protein kinase kinase 4;MAP2K4;mitogen-activated protein kinase kinase 4 |
Definition | JNK activating kinase 1|JNK-activated kinase 1|JNK-activating kinase 1|MAP kinase kinase 4|MAPK/ERK kinase 4|MAPKK 4|MEK 4|SAPK kinase 1|SAPK/ERK kinase 1|c-Jun N-terminal kinase kinase 1|dual specificity mitogen-activated protein kinase kinase 4|stress-a |
Position | 17p11.2 |
Gene Type | protein-coding |
Gene Mutation: | Substitution Insertion & Deletion Other Mutation |
Substitution | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Substitution - coding silent; c.774T>C; 17:11957363-11957363 |
large_intestine | adenocarcinoma; carcinoma |
Indel | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Deletion - Frameshift; c.?_?del?; |
ovary | serous_carcinoma; carcinoma |
Deletion - Frameshift; c.444delT; |
y; breast | carcinoma |
Deletion - Frameshift; c.882delG; 17:11969404-11969404 |
lung | large_cell_carcinoma; carcinoma |
Deletion - Frameshift; c.?_?del?; |
ovary | endometrioid_carcinoma; carcinoma |
Other Mutation | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
breast | ductal_carcinoma; carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
breast | carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
breast | luminal_NS_carcinoma; carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
ovary | carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
biliary_tract; bile_duct | adenocarcinoma; carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
breast | ductal_carcinoma; carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
ovary | serous_carcinoma; carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
ovary | serous_carcinoma; carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
pancreas | ductal_carcinoma; carcinoma |
Whole gene deletion; c.1_1200del1200; 17:11864929-11985302 |
ovary | serous_carcinoma; carcinoma |