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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 7128 |
Name | TNFAIP3 |
Synonymous | A20|OTUD7C|TNFA1P2;tumor necrosis factor, alpha-induced protein 3;TNFAIP3;tumor necrosis factor, alpha-induced protein 3 |
Definition | OTU domain-containing protein 7C|TNF alpha-induced protein 3|TNFAIP3 (A20)|putative DNA-binding protein A20|tumor necrosis factor alpha-induced protein 3|tumor necrosis factor inducible protein A20|zinc finger protein A20 |
Position | 6q23 |
Gene Type | protein-coding |
Gene Mutation: | Substitution Insertion & Deletion Other Mutation |
Substitution | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Substitution - coding silent; c.987G>A; 6:138241262-138241262 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Substitution - coding silent; c.2175G>A; 6:138243951-138243951 |
haematopoietic_and_lymphoid_ti | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma; lymphoid_neoplasm |
Substitution - coding silent; c.465G>A; 6:138237844-138237844 |
haematopoietic_and_lymphoid_ti | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma; lymphoid_neoplasm |
Indel | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Deletion - Frameshift; c.66_67delGG; 6:138234123-138234124 |
haematopoietic_and_lymphoid_ti; lymph_node | Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.2161delT; 6:138243937-138243937 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.748_763del16; 6:138238939-138238954 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.861_861delA; 6:138239961-138239961 |
haematopoietic_and_lymphoid_ti; stomach | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.2238_2239delGG; 6:138244014-138244015 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1295_1296delGC; 6:138241570-138241571 |
haematopoietic_and_lymphoid_ti; lymph_node | nodular_sclerosing; Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.405_406delAC; 6:138237784-138237785 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.436_437delTC; 6:138237815-138237816 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.399_400delAG; 6:138237778-138237779 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1876_1877delCT; 6:138242151-138242152 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1880_1881delGT; 6:138242155-138242156 |
haematopoietic_and_lymphoid_ti; stomach | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.373_382del10; 6:138237752-138237761 |
haematopoietic_and_lymphoid_ti; stomach | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.2290_2290delG; 6:138244066-138244066 |
haematopoietic_and_lymphoid_ti; lymph_node | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.400_401delGA; 6:138237779-138237780 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.520_521delAT; 6:138238551-138238552 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.866_867delAC; 6:138239966-138239967 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.835_836delGA; 6:138239935-138239936 |
haematopoietic_and_lymphoid_ti; central_nervous_system | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.405_406delAC; 6:138237784-138237785 |
haematopoietic_and_lymphoid_ti; central_nervous_system | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.872_872delT; 6:138239972-138239972 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1879_1880delTG; 6:138242154-138242155 |
haematopoietic_and_lymphoid_ti; lymph_node | nodular_sclerosing; Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.971_975delTCATC; 6:138240071-138240075 |
haematopoietic_and_lymphoid_ti; mediastinum | primary_mediastinal_B_cell_lymphoma; diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.835_836delGA; 6:138239935-138239936 |
haematopoietic_and_lymphoid_ti; lymph_node | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.251_251delA; 6:138234308-138234308 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.735_741delATACCCC; 6:138238926-138238932 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.866_867delAC; 6:138239966-138239967 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1758_1809del52; 6:138242033-138242084 |
haematopoietic_and_lymphoid_ti; lymph_node | nodular_sclerosing; Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.399_400delAG; 6:138237778-138237779 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1310_1319del10; 6:138241585-138241594 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.485delG; 6:138237864-138237864 |
haematopoietic_and_lymphoid_ti; lymph_node | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1246_1250delAACAA; 6:138241521-138241525 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1877_1878delTG; 6:138242152-138242153 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.127_134delATGCACCG; 6:138234184-138234191 |
haematopoietic_and_lymphoid_ti | nodular_sclerosing; Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1370delC; 6:138241645-138241645 |
haematopoietic_and_lymphoid_ti; lymph_node | nodular_sclerosing; Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.149_155delTGTTCAG; 6:138234206-138234212 |
haematopoietic_and_lymphoid_ti; lymph_node | nodular_sclerosing; Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.745_751delGTTCTCG; 6:138238936-138238942 |
haematopoietic_and_lymphoid_ti; lymph_node | nodular_sclerosing; Hodgkin_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.274delC; 6:138234331-138234331 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1228_1229delAG; 6:138241503-138241504 |
haematopoietic_and_lymphoid_ti; mediastinum | primary_mediastinal_B_cell_lymphoma; diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1898_1899delAA; 6:138242173-138242174 |
haematopoietic_and_lymphoid_ti; small_intestine | marginal_zone_lymphoma; lymphoid_neoplasm |
Deletion - Frameshift; c.1347_1423del77; 6:138241622-138241698 |
haematopoietic_and_lymphoid_ti; stomach | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Other Mutation | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lymph_node | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lung | MALT_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | plasmablastic_lymphoma; AIDS_related_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lymph_node | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Complex - frameshift; c.1984_1988TGCGG>TTGCCGT; 6:138242978-138242982 |
haematopoietic_and_lymphoid_ti | lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lymph_node | Hodgkin_lymphoma; lymphoid_neoplasm |
Complex - frameshift; c.301_303GGC>A; 6:138237680-138237682 |
haematopoietic_and_lymphoid_ti; skin | marginal_zone_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lymph_node | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lymph_node | follicular_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; spleen | marginal_zone_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lymph_node | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; eye | MALT_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti | diffuse_large_B_cell_lymphoma; lymphoid_neoplasm |
Whole gene deletion; c.1_2373del2373; 6:138234058-138244149 |
haematopoietic_and_lymphoid_ti; lung | marginal_zone_lymphoma; lymphoid_neoplasm |