Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

1654

Name

DDX3X

Synonymous

DBX|DDX14|DDX3|HLP2;DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked;DDX3X;DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

Definition

ATP-dependent RNA helicase DDX3X|CAP-Rf|DEAD box protein 3, X-chromosomal|DEAD box, X isoform|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3|DEAD/H box-3|helicase like protein 2|helicase-like protein 2

Position

Xp11.3-p11.23

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

Rock-1(h) + Aurora-A(h) + DDX3(h) + HLR2(h) <==> Rock-1(h):Aurora-A(h):DDX3(h):HLR2(h) (binding)
HCV-core(HCV) + DDX3(h) <==> HCV-core(HCV):DDX3(h) (binding)
EIF4A2(h) + DDX3(h) <==> EIF4A2(h):DDX3(h) (binding)
ESE-1(h) + DDX3(h) <==> ESE-1(h):DDX3(h) (binding)
SIAHBP1(h) + DDX3(h) <==> SIAHBP1(h):DDX3(h) (binding)
ILK(h) + DDX3(h) <==> ILK(h):DDX3(h) (binding)
RIP5(h) + DDX3(h) <==> RIP5(h):DDX3(h) (binding)
SAP18(h) + DDX3(h) <==> SAP18(h):DDX3(h) (binding)
TRAF6(h) + DDX3(h) <==> TRAF6(h):DDX3(h) (binding)
LC8(h) + DDX3(h) <==> LC8(h):DDX3(h) (binding)
cd40(h) + DDX3(h) <==> cd40(h):DDX3(h) (binding)
ddx1(h) + DDX3(h) + p72(h) + p68(h) + DDX15(h) + NF45(h) + HNRPH1(h) + EWS(h) + TDP43(h) + RN3(m.s.) + HNRPUL1(h) + raly(h) + SRPK1(h) + taf15(h) + TLS(h) + JKTBP(h) + hnRNPM(h) + SAF-A(h) + DRBP76(h) + Gy1(h) <==> ddx1(h):DDX3(h):p72(h):p68(h):DDX15(h):NF45(h):HNRPH1(h):EWS(h):TDP43(h):RN3(m.s.):HNRPUL1(h):raly(h):SRPK1(h):taf15(h):TLS(h):JKTBP(h):hnRNPM(h):SAF-A(h):DRBP76(h):Gy1(h) (binding)
DDX3X(h) --> DDX3(h) (expression).
HCV-Core-1B-Japanese(HCV1BJapan) + DDX3(h) <==> HCV-Core-1B-Japanese(HCV1BJapan):DDX3(h) (binding)
DDX3(h) + HCV-Core-1B-Japanese(HCV1BJapan) <==> DDX3(h):HCV-Core-1B-Japanese(HCV1BJapan) (binding)
DDX3(h) --> DDX3(h) (translocation)
DDX3(h) + HCV-core(HCV) <==> DDX3(h):HCV-core(HCV) (binding)
DDX3(h) --> DDX3(h) (translocation)
DDX3X(h) --> DDX3(h) (expression).
DDX3(h) --> DDX3(h) (translocation)
DDX3(h) --> DDX3(h) (translocation)

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

2N-acetylserine.Swiss-Prot 53.0
69Phosphotyrosine.Swiss-Prot 53.0
74Phosphoserine (By similarity).Swiss-Prot 53.0
104Phosphotyrosine.Swiss-Prot 53.0
343Phosphotyrosine.Swiss-Prot 53.0
103Phosphotyrosine15592455Phospho.ELM 6.0
73Phosphoserine14729942Phospho.ELM 6.0
68Phosphotyrosine15592455;16094384Phospho.ELM 6.0
342Phosphotyrosine16097034Phospho.ELM 6.0
203Phosphothreonine (CDK1)16280325Phospho.ELM 6.0
322Phosphothreonine (CDK1)16280325Phospho.ELM 6.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chrX

Promoter: 41076095 - 41078095Agilent_014791

chrX

Promoter: 41076095 - 41078095GSE27584

chrX

Promoter: 41076095 - 41078095Agilent_014791_44K


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