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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 219699 |
Name | UNC5B |
Synonymous | UNC5H2|p53RDL1;unc-5 homolog B (C. elegans);UNC5B;unc-5 homolog B (C. elegans) |
Definition | netrin receptor UNC5B|p53-regulated receptor for death and life protein 1|protein unc-5 homolog 2|protein unc-5 homolog B|transmembrane receptor Unc5H2|unc-5 homolog 2 |
Position | 10q22.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
PIKE(m.s.) + unc-5B-isoform1(h) <==> PIKE(m.s.):unc-5B-isoform1(h) (binding) | unc-5B-isoform1(h) + ATP --> unc-5B-isoform1(h){pY} + ADP (phosphorylation) | UNC5B(h) --> unc-5B-isoform1(h) (expression). | G-alpha-i2(m) + unc-5B(h) <==> G-alpha-i2(m):unc-5B(h) (binding) | unc-5B(h) + G-alpha-i2(m):GTP <==> unc-5B(h):G-alpha-i2(m):GTP (binding) | unc-5B(h) + PIKE(m.s.) <==> unc-5B(h):PIKE(m.s.) (binding) | UNC5B(h) --> unc-5B(h) (expression). | UNC5B(h) --> unc-5B-isoform2(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
Location (AA) |
PTM type |
Literature |
Database |
222 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 347 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
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chr10 |
Promoter: 72640855 - 72642855 | Agilent_014791 |
chr10 |
Promoter: 72640855 - 72642855 | GSE27584 |
chr10 |
Promoter: 72640855 - 72642855 | Agilent_014791_44K |
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