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| General information | Expression | Regulation | Mutation | Interaction |
Basic Information | |
|---|---|
Gene ID | 2444 |
Name | FRK |
Synonymous | GTK|PTK5|RAK;fyn-related kinase;FRK;fyn-related kinase |
Definition | PTK5 protein tyrosine kinase 5|nuclear tyrosine protein kinase RAK|protein-tyrosine kinase 5|tyrosine-protein kinase FRK |
Position | 6q21-q22.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database | FRK(h) --> BSK(h) (expression). | ErbB2(h){pY1222} + BSK(h) <==> ErbB2(h){pY1222}:BSK(h) (binding) | ErbB4(h) + BSK(h) <==> ErbB4(h):BSK(h) (binding) | FRK(h) --> BSK(h) (expression). |
|---|
Post Transcriptional Modification From dbPTM | | Top | |
Location (AA) | PTM type | Literature | Database | 387 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 497 | Phosphotyrosine. | Swiss-Prot 53.0 | 497 | Phosphotyrosine | 15951569 | Phospho.ELM 6.0 |
|---|
Methylation Profile From DiseaseMeth database | | Top | |
Chromosome | Location | Source |
|---|---|---|
chr6 |
Promoter: 116488114 - 116490114 | GoldenGate_Methylation_Cancer_Panel_I |
chr6 |
Promoter: 116488114 - 116490114 | GSE27584 |