Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

274

Name

BIN1

Synonymous

AMPH2|AMPHL|SH3P9;bridging integrator 1;BIN1;bridging integrator 1

Definition

amphiphysin II|amphiphysin-like protein|box dependant MYC interacting protein 1|box-dependent myc-interacting protein 1|myc box-dependent-interacting protein 1

Position

2q14

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

Bin1-Isoform-1(h) + c-Myc(h) <==> Bin1-Isoform-1(h):c-Myc(h) (binding).
BIN1(h) --> Bin1-Isoform-1(h) (expression).
amphiphysin2b-1(h) + p73beta(h) <==> amphiphysin2b-1(h):p73beta(h) (binding)
BIN1(h) --> amphiphysin2b-1(h) (expression).
p73beta(h) --> CDKN1A(h) (transactivation)
amphiphysin2(h) + FAK1(r) <==> amphiphysin2(h):FAK1(r) (binding)
HCV-NS5A-1B(HCV1B) + amphiphysin2(h) <==> HCV-NS5A-1B(HCV1B):amphiphysin2(h) (binding)
POB1-isoform2(h) + amphiphysin2(h) <==> POB1-isoform2(h):amphiphysin2(h) (binding)
BIN1(h) --> amphiphysin2(h) (expression).
BIN1(h) --> Amphiphysin2A(h) (expression).
BIN1(h) --> Amphiphysin-IIB(h) (expression).
BIN1(h) --> Amphiphysin-IIC1(h) (expression).
BIN1(h) --> Amphiphysin-IIC2(h) (expression).
BIN1(h) --> Amphiphysin-IID(h) (expression).
HCV-NS5A-1B(HCV1B) + Amphiphysin-II2(h) <==> HCV-NS5A-1B(HCV1B):Amphiphysin-II2(h) (binding)
BIN1(h) --> Amphiphysin-II2(h) (expression).
BIN1(h) --> Amphiphysin-II3(h) (expression).
BIN1(h) --> Amphiphysin-BIN1(h) (expression).
BIN1(h) --> Amphiphysin-BIN1-10-13(h) (expression).
BIN1(h) --> Amphiphysin-BIN1-13(h) (expression).
BIN1(h) --> Amphiphysin-BIN1+12A(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

296Phosphoserine.Swiss-Prot 53.0
298Phosphoserine.Swiss-Prot 53.0
303Phosphoserine.Swiss-Prot 53.0
307Phosphothreonine (By similarity).Swiss-Prot 53.0
331Phosphoserine.Swiss-Prot 53.0
298Phosphoserine15302935;17081983Phospho.ELM 6.0
296Phosphoserine15302935;17081983Phospho.ELM 6.0
303Phosphoserine15302935;17081983Phospho.ELM 6.0
307Phosphothreonine17081983Phospho.ELM 6.0
331Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr2

Promoter: 127580834 - 127582834Agilent_014791

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834GSE27584

chr2

Promoter: 127580834 - 127582834Agilent_014791_44K


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