Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3685

Name

ITGAV

Synonymous

CD51|MSK8|VNRA;integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51);ITGAV;integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Definition

antigen identified by monoclonal antibody L230|integrin alpha-V|vitronectin receptor subunit alpha

Position

2q31-q32

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

CD51(h) + beta6-integrin(h) + LAP3(h) <==> CD51(h):beta6-integrin(h):LAP3(h) (binding)
LAP1(mo) + CD51(h) + beta1-integrin(h) <==> LAP1(mo):CD51(h):beta1-integrin(h) (binding)
LAP1(mo) + CD51(h) + beta5-integrin(h) <==> LAP1(mo):CD51(h):beta5-integrin(h) (binding)
LAP1(mo) + CD51(h) <==> LAP1(mo):CD51(h) (binding)
LAP1(h) + CD51(h) + beta1-integrin(h) <==> LAP1(h):CD51(h):beta1-integrin(h) (binding)
LAP1(h) + CD51(h) + beta3-integrin(h) <==> LAP1(h):CD51(h):beta3-integrin(h) (binding)
LAP1(h) + CD51(h) + beta5-integrin(h) <==> LAP1(h):CD51(h):beta5-integrin(h) (binding)
LAP1(h) + CD51(h) + beta6-integrin(h) <==> LAP1(h):CD51(h):beta6-integrin(h) (binding)
Cas(h) + EGFR(h) + CD51(h) + beta3-integrin(h) + Src(h) <==> Cas(h):EGFR(h):CD51(h):beta3-integrin(h):Src(h) (binding)
CAML1(m.s.) + CD51(h) <==> CAML1(m.s.):CD51(h) (binding)
CD51(h) + aup-1-isoformS(h) <==> CD51(h):aup-1-isoformS(h) (binding)
ITGAV(h) --> CD51(h) (expression).
beta3-integrin(h) + CD51-isoform1(h) <==> beta3-integrin(h):CD51-isoform1(h) (binding)
ITGAV(h) --> CD51-isoform1(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

74N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
290N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
296N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
488N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
554N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
615N-linked (GlcNAc...).Swiss-Prot 53.0
704N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
835N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
851N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
874N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
945N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
973N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
980N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr2

Promoter: 187161545 - 187163545Agilent_014791

chr2

Promoter: 187161545 - 187163545GSE27584

chr2

Promoter: 187161545 - 187163545Agilent_014791_44K


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