Basic Information
Gene ID	3690
Name	ITGB3
Synonymous	BDPLT2\|CD61\|GP3A\|GPIIIa\|GT;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61);ITGB3;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Definition	integrin beta-3\|platelet glycoprotein IIIa\|platelet membrane glycoprotein IIIa
Position	17q21.32
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database
VEGFR-2(h) + beta3-integrin(h) <==> VEGFR-2(h):beta3-integrin(h) (binding)
LAP1(h) + CD51(h) + beta3-integrin(h) <==> LAP1(h):CD51(h):beta3-integrin(h) (binding)
beta3-integrin(h) + beta3-endonexin(h) <==> beta3-integrin(h):beta3-endonexin(h) (binding)
beta3-integrin(h) + talin(h) <==> beta3-integrin(h):talin(h) (binding)
beta3-integrin(h) + Syk(h) <==> beta3-integrin(h):Syk(h) (binding)
beta3-integrin(h) + ABP-280(h) <==> beta3-integrin(h):ABP-280(h) (binding)
beta3-integrin(h) + ZAP-70(h) <==> beta3-integrin(h):ZAP-70(h) (binding)
Cas(h) + EGFR(h) + CD51(h) + beta3-integrin(h) + Src(h) <==> Cas(h):EGFR(h):CD51(h):beta3-integrin(h):Src(h) (binding)
TGC(h) + beta3-integrin(h) <==> TGC(h):beta3-integrin(h) (binding)
beta3-integrin(h) + fibronectin(m.s.) <==> beta3-integrin(h):fibronectin(m.s.) (binding)
beta3-integrin(h) + Fibronectin-p42(m.s.) <==> beta3-integrin(h):Fibronectin-p42(m.s.) (binding)
beta3-integrin(h) + CD51-isoform1(h) <==> beta3-integrin(h):CD51-isoform1(h) (binding)
ITGB3(h) --> beta3-integrin(h) (expression).
GP1BB(h) --> beta3-integrin(h) (binding)
ITGB3(h) --> beta3A-integrin(h) (expression).
ITGB3(h) --> beta3B-integrin(h) (expression).
ITGB3(h) --> beta3C-integrin(h) (expression).

Location (AA)	PTM type	Literature	Database
125	N-linked (GlcNAc...).		Swiss-Prot 53.0
346	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
397	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
478	N-linked (GlcNAc...).		Swiss-Prot 53.0
585	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
680	N-linked (GlcNAc...).		Swiss-Prot 53.0
773	Phosphotyrosine.		Swiss-Prot 53.0
779	Phosphothreonine; by PDPK1 and PKB/AKT1;in vitro.		Swiss-Prot 53.0
785	Phosphotyrosine.		Swiss-Prot 53.0
773	Phosphotyrosine (Syk;Src)	8631894;15699036	Phospho.ELM 6.0
785	Phosphotyrosine (Syk;Src)	8631894	Phospho.ELM 6.0
779	Phosphothreonine (PDK-1)	10896934	Phospho.ELM 6.0
777	Phosphothreonine (PDK-1)	10896934	Phospho.ELM 6.0