Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

387

Name

RHOA

Synonymous

ARH12|ARHA|RHO12|RHOH12;ras homolog gene family, member A;RHOA;ras homolog gene family, member A

Definition

Aplysia ras-related homolog 12|h12|oncogene RHO H12|rho cDNA clone 12|small GTP binding protein RhoA|transforming protein RhoA

Position

3p21.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

RhoA(h) + RhoGEF(m) <==> RhoA(h):RhoGEF(m) (binding)
RhoA(h) + RhoGEF(mo) <==> RhoA(h):RhoGEF(mo) (binding)
RhoA(h) + RhoGAP5(m){p} <==> RhoA(h):RhoGAP5(m){p} (binding)
RhoA(h) + RhoGDI-2(h) <==> RhoA(h):RhoGDI-2(h) (binding)
IL-1RI(h) + RhoA(h) <==> IL-1RI(h):RhoA(h) (binding)
RhoA(h) + RhoGDI-1(h) <==> RhoA(h):RhoGDI-1(h) (binding)
RhoA(h) + AKAP13-Lbc(h) <==> RhoA(h):AKAP13-Lbc(h) (binding)
RhoA(h) + AKAP13-Lbc(h) + PKA-RII(h) <==> RhoA(h):AKAP13-Lbc(h):PKA-RII(h) (binding)
RhoA(h) + Kv1.2(m.s.) <==> RhoA(h):Kv1.2(m.s.) (binding)
AKAP13(h) + RhoA(h) <==> AKAP13(h):RhoA(h) (binding)
RhoA(h) + BPGAP1(h) <==> RhoA(h):BPGAP1(h) (binding)
RhoA(h) + RhoGDI(h) <==> RhoA(h):RhoGDI(h) (binding)
BNIP-2(h) + RhoA(h) <==> BNIP-2(h):RhoA(h) (binding)
plk1(h) + RhoA(h) <==> plk1(h):RhoA(h) (binding)
RhoA(h) + RhoGAP1(h) <==> RhoA(h):RhoGAP1(h) (binding)
RHOA(h) --> RhoA(h) (expression).
P2RX7(h) --> RhoA(h) (activation)
Ost(m.s.) --> RhoA(h) (increase of exchange)
arhgef5(h) --> RhoA(h) (increase of exchange)
LAMA5(h) --> RhoA(h) (activation)
VLA-2(h) --> RhoA(h) (activation)
fibronectin(m.s.) --> RhoA(h) (regulation of localization)
alpha5-integrin(m.s.) --> RhoA(h) (regulation of localization)
beta1-integrin(m.s.) --> RhoA(h) (regulation of localization)
RHOA(h) --> RhoA(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

41ADP-ribosylasparagine (by botulinumtoxin) (Probable).Swiss-Prot 53.0
190Cysteine methyl ester.Swiss-Prot 53.0
190S-geranylgeranyl cysteine.Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr3

Promoter: 49424030 - 49426030GSE27584

chr3

Promoter: 49424030 - 49426030Agilent_014791_44K

chr3

Promoter: 49424030 - 49426030Agilent_014791


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