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| General information | Expression | Regulation | Mutation | Interaction |
Basic Information | |
|---|---|
Gene ID | 4771 |
Name | NF2 |
Synonymous | ACN|BANF|SCH;neurofibromin 2 (merlin);NF2;neurofibromin 2 (merlin) |
Definition | merlin|moesin-ezrin-radixin like|moesin-ezrin-radixin-like protein|moesin-ezrin-radizin-like protein|neurofibromin 2 (bilateral acoustic neuroma)|neurofibromin-2|schwannomerlin|schwannomin |
Position | 22q12.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database | CD44(h) + Merlin(h) <==> CD44(h):Merlin(h) (binding) | Merlin(h) + ATP --> Merlin(h){pS} + ADP (phosphorylation) | NF2(h) --> Merlin(h) (expression). | p65PAK(m.s.) + Merlin-isoform1(h) <==> p65PAK(m.s.):Merlin-isoform1(h) (binding) | Merlin-isoform1(h) + p65PAK(r) <==> Merlin-isoform1(h):p65PAK(r) (binding) | NF2(h) --> Merlin-isoform1(h) (expression). | NF2(h) --> Merlin-isoform2(h) (expression). | NF2(h) --> Merlin-isoform3(h) (expression). | NF2(h) --> Merlin-isoform4(h) (expression). | NF2(h) --> Merlin-isoform5(h) (expression). | NF2(h) --> Merlin-isoform6(h) (expression). | NF2(h) --> Merlin-isoform7(h) (expression). | NF2(h) --> Merlin-isoform8(h) (expression). | NF2(h) --> Merlin-isoform9(h) (expression). | NF2(h) --> Merlin-isoform10(h) (expression). |
|---|
Post Transcriptional Modification From dbPTM | | Top | |
Location (AA) | PTM type | Literature | Database | 518 | Phosphoserine. | Swiss-Prot 53.0 |
|---|
Methylation Profile From DiseaseMeth database | | Top | |
Chromosome | Location | Source |
|---|---|---|
chr22 |
Promoter: 28328065 - 28330065 | Agilent_014791 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | GSE27584 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:16353169 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:15609345 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |
chr22 |
Promoter: 28328065 - 28330065 | PMID:14654541 |