Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

5074

Name

PAWR

Synonymous

PAR4|Par-4;PRKC, apoptosis, WT1, regulator;PAWR;PRKC, apoptosis, WT1, regulator

Definition

PRKC apoptosis WT1 regulator protein|WT1-interacting protein|prostate apoptosis response 4 protein|prostate apoptosis response protein 4|prostate apoptosis response protein PAR-4|transcriptional repressor PAR4

Position

12q21

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

   | Top |

Regulation From TransFac database

pawr(h) + PKCzeta(r) <==> pawr(h):PKCzeta(r) (binding)
pawr(h) + PKCiota(x) <==> pawr(h):PKCiota(x) (binding)
pawr(h) + WT1(h) <==> pawr(h):WT1(h) (binding)
pawr(h) + ZIPK(h) <==> pawr(h):ZIPK(h) (binding)
D2-isoform1(h) + pawr(h) <==> D2-isoform1(h):pawr(h) (binding)
D2(h) + pawr(h) <==> D2(h):pawr(h) (binding)
pawr(h) + E2F-1(h) <==> pawr(h):E2F-1(h) (binding)
ICEN22(h) + pawr(h) <==> ICEN22(h):pawr(h) (binding)
PAWR(h) --> pawr(h) (expression).
D2-isoform1(h) + pawr(h) <==> D2-isoform1(h):pawr(h) (binding)
pawr(h) + E2F-1(h) <==> pawr(h):E2F-1(h) (binding)
pawr(h) --> DIABLO(h) (transactivation)
PAWR(h) --> pawr(h) (expression).

Post Transcriptional Modification From dbPTM

   | Top |

Location (AA)

PTM type

Literature

Database

163Phosphothreonine (by PKA) (Bysimilarity).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

   | Top |

Chromosome

Location

Source

chr12

Promoter: 78608421 - 78610421Agilent_014791

chr12

Promoter: 78608421 - 78610421GSE27584

chr12

Promoter: 78608421 - 78610421Agilent_014791_44K


Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston Rights Reserved
Site Policies | State of Texas