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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 5573 |
Name | PRKAR1A |
Synonymous | ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1;protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1);PRKAR1A;protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) |
Definition | cAMP-dependent protein kinase regulatory subunit RIalpha|cAMP-dependent protein kinase type I-alpha regulatory chain|cAMP-dependent protein kinase type I-alpha regulatory subunit|protein kinase A type 1a regulatory subunit|tissue-specific extinguisher 1 |
Position | 17q23-q24 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
NPRL2(h) + PKA-RI-alpha(h) <==> NPRL2(h):PKA-RI-alpha(h) (binding) | PKA-RI-alpha(h) + PKACA(h) <==> PKA-RI-alpha(h):PKACA(h) (binding) | PKA-RI-alpha(h) + Ubc12(h) <==> PKA-RI-alpha(h):Ubc12(h) (binding) | nuak1(h) + PKA-RI-alpha(h) <==> nuak1(h):PKA-RI-alpha(h) (binding) | MCRS1(h) + PKA-RI-alpha(h) <==> MCRS1(h):PKA-RI-alpha(h) (binding) | PKA-RI-alpha(h) + PRKA10(h) <==> PKA-RI-alpha(h):PRKA10(h) (binding) | PKA-RI-alpha(h) + ASC(h) <==> PKA-RI-alpha(h):ASC(h) (binding) | PKA-RI-alpha(h) + plekhf2(h) <==> PKA-RI-alpha(h):plekhf2(h) (binding) | PKA-RI-alpha(h) + MGC13057(h) <==> PKA-RI-alpha(h):MGC13057(h) (binding) | RSK1(r) + PKA-RI-alpha(h) <==> RSK1(r):PKA-RI-alpha(h) (binding) | PKA-RI-alpha(h) + PKAc(h) <==> PKA-RI-alpha(h):PKAc(h) (binding) | PRKAR1A(h) --> PKA-RI-alpha(h) (expression). | PKA-RI-alpha(h):PKAc(h) <==> PKA-RI-alpha(h) + PKAc(h) (dissociation) | PKA-RI-alpha(h) + calmodulin(b) <==> PKA-RI-alpha(h):calmodulin(b) (binding) | PRKAR1A(h) --> PKA-RI-alpha(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
1 | N-acetylmethionine. | Swiss-Prot 53.0 | 77 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 83 | Phosphoserine. | Swiss-Prot 53.0 | 101 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 83 | Phosphoserine | 15572359;17081983 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
|---|---|---|
chr17 |
Promoter: 64018638 - 64020638 | Agilent_014791 |
chr17 |
Promoter: 64018205 - 64020205 | Agilent_014791 |
chr17 |
Promoter: 64018638 - 64020638 | GoldenGate_Methylation_Cancer_Panel_I |
chr17 |
Promoter: 64018205 - 64020205 | GoldenGate_Methylation_Cancer_Panel_I |
chr17 |
Promoter: 64018638 - 64020638 | GoldenGate_Methylation_Cancer_Panel_I |
chr17 |
Promoter: 64018638 - 64020638 | GSE27584 |
chr17 |
Promoter: 64018205 - 64020205 | GSE27584 |
chr17 |
Promoter: 64018638 - 64020638 | GSE27584 |
chr17 |
Promoter: 64018638 - 64020638 | Agilent_014791_44K |