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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 55743 |
Name | CHFR |
Synonymous | RNF116|RNF196;checkpoint with forkhead and ring finger domains;CHFR;checkpoint with forkhead and ring finger domains |
Definition | E3 ubiquitin-protein ligase CHFR|RING finger protein 196|checkpoint with forkhead and RING finger domains protein |
Position | 12q24.33 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
|
Regulation From TransFac database |
CHFR(h) --> Chfr-isoform1(h) (expression). | Aurora-A(h) + Chfr(h) <==> Aurora-A(h):Chfr(h) (binding) | HDAC1(m.s.) + Chfr(h) <==> HDAC1(m.s.):Chfr(h) (binding) | HDAC1(h) + Chfr(h) <==> HDAC1(h):Chfr(h) (binding) | Chfr(h) + Aurora-A(m.s.) <==> Chfr(h):Aurora-A(m.s.) (binding) | plk1(m.s.) + Chfr(h) <==> plk1(m.s.):Chfr(h) (binding) | Chfr(h) --> histone H4(h){ace} (increase of acetylation) | Chfr(h) --> p53(m.s.){ace} (increase of acetylation) | hdac2(m.s.) + Chfr(h) <==> hdac2(m.s.):Chfr(h) (binding) | Chfr(h) --> KAI1(h) (increase of abundance) | Chfr(h) --> E-cadherin(h) (increase of abundance) | Chfr(h) --> CD82(h) (transactivation) | Chfr(h) --> CDH1(h) (transactivation) | Chfr(h) --> CDKN1A(h) (transactivation) | Chfr(h) --> p21Cip1(h) (increase of abundance) | CHFR(h) --> Chfr(h) (expression). | HDAC1(m.s.) + n ubiquitin(m.s.) --Chfr(h)--> HDAC1(m.s.){ub}n (ubiquitination) | HDAC1(h) + n ubiquitin(h) --Chfr(h)--> HDAC1(h){ub}n (ubiquitination) | CHFR(h) --> Chfr-isoform2(h) (expression). | CHFR(h) --> Chfr-isoform3(h) (expression). | CHFR(h) --> Chfr-isoform4(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
There is no record for CHFR |
Methylation Profile From DiseaseMeth database | | Top | |
|
Chromosome |
Location |
Source |
|---|---|---|
chr12 |
Promoter: 131973757 - 131975757 | Agilent_014791 |
chr12 |
Promoter: 131973757 - 131975757 | GoldenGate_Methylation_Cancer_Panel_I |
chr12 |
Promoter: 131973757 - 131975757 | GSE27584 |
chr12 |
Promoter: 131973757 - 131975757 | Agilent_014791_44K |
chr12 |
Promoter: 131973757 - 131975757 | PMID:15201973 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:16827108 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:15138487 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:16475678 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:16568372 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:15735977 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:15760919 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:12538348 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:17201143 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:12810945 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:16201259 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:15897551 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:15471559 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:16334792 |
chr12 |
Promoter: 131973757 - 131975757 | PMID:15937956 |