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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 5653 |
Name | KLK6 |
Synonymous | Bssp|Klk7|PRSS18|PRSS9|SP59|hK6;kallikrein-related peptidase 6;KLK6;kallikrein-related peptidase 6 |
Definition | kallikrein-6|neurosin|protease M|serine protease 18|serine protease 9|zyme |
Position | 19q13.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
kallikrein-6(h) --> kallikrein-6-E77(h) + protein remnants (cleavage; automodification) | Antithrombin-III(h) + kallikrein-6(h) <==> Antithrombin-III(h):kallikrein-6(h) (binding) | kallikrein-6(h) + alpha-2-antiplasmin(h) <==> kallikrein-6(h):alpha-2-antiplasmin(h) (binding) | KLK6(h) --> kallikrein-6(h) (expression). | NACP(h) --kallikrein-6(h)--> protein remnants (degradation) | fibrinogen-alpha(h) --kallikrein-6(h)--> protein remnants (degradation) | collagen-I(b) --kallikrein-6(h)--> protein remnants (degradation) | collagen-IV(h) --kallikrein-6(h)--> protein remnants (degradation) | fibrinogen-beta(h) --kallikrein-6(h)--> protein remnants (degradation) | APP(m.s.) --kallikrein-6(h)--> protein remnants (degradation) | KLK6(h) --> kallikrein-6(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
Location (AA) |
PTM type |
Literature |
Database |
134 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
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chr19 |
Promoter: 56164241 - 56166241 | GSE27584 |
chr19 |
Promoter: 56163359 - 56165359 | GSE27584 |
chr19 |
Promoter: 56163359 - 56165359 | GSE27584 |
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