Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

5653

Name

KLK6

Synonymous

Bssp|Klk7|PRSS18|PRSS9|SP59|hK6;kallikrein-related peptidase 6;KLK6;kallikrein-related peptidase 6

Definition

kallikrein-6|neurosin|protease M|serine protease 18|serine protease 9|zyme

Position

19q13.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

kallikrein-6(h) --> kallikrein-6-E77(h) + protein remnants (cleavage; automodification)
Antithrombin-III(h) + kallikrein-6(h) <==> Antithrombin-III(h):kallikrein-6(h) (binding)
kallikrein-6(h) + alpha-2-antiplasmin(h) <==> kallikrein-6(h):alpha-2-antiplasmin(h) (binding)
KLK6(h) --> kallikrein-6(h) (expression).
NACP(h) --kallikrein-6(h)--> protein remnants (degradation)
fibrinogen-alpha(h) --kallikrein-6(h)--> protein remnants (degradation)
collagen-I(b) --kallikrein-6(h)--> protein remnants (degradation)
collagen-IV(h) --kallikrein-6(h)--> protein remnants (degradation)
fibrinogen-beta(h) --kallikrein-6(h)--> protein remnants (degradation)
APP(m.s.) --kallikrein-6(h)--> protein remnants (degradation)
KLK6(h) --> kallikrein-6(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

134N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr19

Promoter: 56164241 - 56166241GSE27584

chr19

Promoter: 56163359 - 56165359GSE27584

chr19

Promoter: 56163359 - 56165359GSE27584


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