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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 5771 |
Name | PTPN2 |
Synonymous | PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP;protein tyrosine phosphatase, non-receptor type 2;PTPN2;protein tyrosine phosphatase, non-receptor type 2 |
Definition | T-cell protein tyrosine phosphatase|tyrosine-protein phosphatase non-receptor type 2 |
Position | 18p11.3-p11.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
TC-PTPb(h) + importin-beta1(h) <==> TC-PTPb(h):importin-beta1(h) (binding) | PTPN2(h) --> TC-PTPb(h) (expression). | TC-PTPa(h) + importin-beta1(h) <==> TC-PTPa(h):importin-beta1(h) (binding) | PTPN2(h) --> TC-PTPa(h) (expression). | Shc-1-p52(h){p} --TC-PTPa(h)--> Shc-1-p52(h) + p (dephosphorylation) | 14-3-3sigma(m.s.) + TC-PTP(h) <==> 14-3-3sigma(m.s.):TC-PTP(h) (binding) | PTPN2(h) --> TC-PTP(h) (expression). | STAT1(h){pY701} --TC-PTP(h)--> STAT1(h) + p (dephosphorylation) |
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Post Transcriptional Modification From dbPTM | | Top | |
There is no record for PTPN2 |
Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
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chr18 |
Promoter: 12873834 - 12875834 | Agilent_014791 |
chr18 |
Promoter: 12873834 - 12875834 | GSE27584 |
chr18 |
Promoter: 12873834 - 12875834 | GSE27584 |
chr18 |
Promoter: 12873834 - 12875834 | GSE27584 |
chr18 |
Promoter: 12873834 - 12875834 | Agilent_014791_44K |
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