Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

6282

Name

S100A11

Synonymous

MLN70|S100C;S100 calcium binding protein A11;S100A11;S100 calcium binding protein A11

Definition

MLN 70|S100 calcium-binding protein A11 (calgizzarin)|calgizzarin|metastatic lymph node gene 70 protein|protein S100-A11|protein S100-C

Position

1q21

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

s100a11(h) --> AKT(h){p} (increase of phosphorylation)
s100a11(h) --> Bcl-2(h) (increase of abundance)
s100a11(h) --/ p21Cip1(h) (decrease of abundance)
s100a11(h) --/ p27Kip1(h) (decrease of abundance)
s100a11(h) --> s100a11(h) (expression).
s100a11(h) + ATP --PKCalpha(rb)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) + ATP --PKCdelta(m)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) + ATP --PKCepsilon(m.s.)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) + ATP --PKCeta(m)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) --> s100a11(h) (expression).
EGF(h) --> s100a11(h) (increase of abundance)
Ca --> s100a11(h) (increase of abundance)
GROalpha(h) --> s100a11(h) (increase of abundance)
TGFalpha(h) --> s100a11(h) (increase of abundance)

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

6Phosphoserine.Swiss-Prot 53.0
94Phosphoserine14623863Phospho.ELM 6.0
10Phosphothreonine10851017;14623863Phospho.ELM 6.0
6Phosphoserine15302935;17081983Phospho.ELM 6.0
71Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr1

Promoter: 150275635 - 150277635GSE27584

chr1

Promoter: 150275635 - 150277635E-GEOD-20553


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