Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

6477

Name

SIAH1

Synonymous

SIAH1A;seven in absentia homolog 1 (Drosophila);SIAH1;seven in absentia homolog 1 (Drosophila)

Definition

E3 ubiquitin-protein ligase SIAH1|siah-1a

Position

16q12

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

   | Top |

Regulation From TransFac database

apc(h) + Siah1(h) <==> apc(h):Siah1(h) (binding)
Siah1(h) + SIAHBP1(h) <==> Siah1(h):SIAHBP1(h) (binding)
Siah1(h) + SIP-S(h) <==> Siah1(h):SIP-S(h) (binding)
Siah1(h) + SIAHBP1(h) + Skp1(h) <==> Siah1(h):SIAHBP1(h):Skp1(h) (binding)
Ebi(h) + Siah1(h) + SIAHBP1(h) + Skp1(h) <==> Ebi(h):Skp1(h):Siah1(h):SIAHBP1(h) (binding)
bag1(m) + Siah1(h) <==> bag1(m):Siah1(h) (binding)
2 Siah1(h) <==> Siah1(h):Siah1(h) (binding)
Siah1(h) + Ubc9(h) <==> Siah1(h):Ubc9(h) (binding)
Siah1(h) --/ DCC(h) (degradation)
Numb(h) + Siah1(h) <==> Numb(h):Siah1(h) (binding)
Siah1(h) + Synphilin-1(h) <==> Siah1(h):Synphilin-1(h) (binding)
Siah1(h) + synphilin-1(r) <==> Siah1(h):synphilin-1(r) (binding)
Siah1(h) + n ubiquitin(v.s.) --> Siah1(h){ub(n)} (ubiquitination)
Kid(m.s.) + Siah1(h) <==> Kid(m.s.):Siah1(h) (binding)
Siah1(h) + SLM2(h) <==> Siah1(h):SLM2(h) (binding)
Siah1(h) + aff4(h) <==> Siah1(h):aff4(h) (binding)
p53(h) --> Siah1(h) (activation)
SIAH1(h) --> Siah1(h) (expression).
Synphilin-1(h) + n ubiquitin(v.s.) --Siah1(h),ATP--> Synphilin-1(h){ub(n)} (ubiquitination)
Synphilin-1(h) + n ubiquitin(v.s.) --ATP,E1(v.s.),Ubc5B(h),Siah1(h)--> Synphilin-1(h){ub(n)} (ubiquitination)
SIAH1(h) --> Siah1-isoform1(h) (expression).
SIAH1(h) --> Siah1-isoform2(h) (expression).
SIAH1(h) --> Siah1-isoform3(h) (expression).

Post Transcriptional Modification From dbPTM

   | Top |

There is no record for SIAH1

Methylation Profile From DiseaseMeth database

   | Top |

Chromosome

Location

Source

chr16

Promoter: 46956785 - 46958785Agilent_014791

chr16

Promoter: 46976230 - 46978230Agilent_014791

chr16

Promoter: 46976230 - 46978230GSE27584

chr16

Promoter: 46956785 - 46958785GSE27584

chr16

Promoter: 46976230 - 46978230Agilent_014791_44K

chr16

Promoter: 46956785 - 46958785Agilent_014791

chr16

Promoter: 46976230 - 46978230Agilent_014791


Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston Rights Reserved
Site Policies | State of Texas