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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 7414 |
Name | VCL |
Synonymous | CMD1W|CMH15|MVCL;vinculin;VCL;vinculin |
Definition | metavinculin |
Position | 10q22.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
FAK1(h) + vinculin(h) <==> FAK1(h):vinculin(h) (binding) | vinculin(h) + ATP --> vinculin(h){pY} + ADP (phosphorylation) | trip6(h) + vinculin(h) <==> trip6(h):vinculin(h) (binding) | vinculin(h) + abi2(h) <==> vinculin(h):abi2(h) (binding) | vinculin(h) + c19orf57(h) <==> vinculin(h):c19orf57(h) (binding) | VCL(h) --> vinculin(h) (expression). | VCL(h) --> Vinculin-isoform1(h) (expression). | VCL(h) --> Vinculin-isoform2(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
Location (AA) |
PTM type |
Literature |
Database |
290 | Phosphoserine. | Swiss-Prot 53.0 | 508 | Phosphothreonine. | Swiss-Prot 53.0 | 537 | Phosphotyrosine (Potential). | Swiss-Prot 53.0 | 604 | Phosphothreonine. | Swiss-Prot 53.0 | 721 | Phosphoserine. | Swiss-Prot 53.0 | 822 | Phosphotyrosine (Probable). | Swiss-Prot 53.0 | 1100 | Phosphoserine (PKC alpha) | 11741957 | Phospho.ELM 6.0 | 1112 | Phosphoserine (PKC alpha) | 11741957 | Phospho.ELM 6.0 | 507 | Phosphothreonine | 16097034 | Phospho.ELM 6.0 | 1132 | Phosphotyrosine | 15229287 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
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chr10 |
Promoter: 75426378 - 75428378 | Agilent_014791 |
chr10 |
Promoter: 75426378 - 75428378 | GSE27584 |
chr10 |
Promoter: 75426378 - 75428378 | GSE27584 |
chr10 |
Promoter: 75426378 - 75428378 | Agilent_014791_44K |
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