Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

84152

Name

PPP1R1B

Synonymous

DARPP-32|DARPP32;protein phosphatase 1, regulatory (inhibitor) subunit 1B;PPP1R1B;protein phosphatase 1, regulatory (inhibitor) subunit 1B

Definition

dopamine and cAMP-regulated neuronal phosphoprotein 32|protein phosphatase 1 regulatory subunit 1B

Position

17q12

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

   | Top |

Regulation From TransFac database

PPP1R1B(h) --> DARPP32-isoform1(h) (expression).
DARPP32(h) + ATP --> DARPP32(h){pT34} + ADP (phosphorylation)
PPP1R1B(h) --> DARPP32(h) (expression).
PPP1R1B(h) --> DARPP32-isoform2(h) (expression).

Post Transcriptional Modification From dbPTM

   | Top |

Location (AA)

PTM type

Literature

Database

1N-acetylmethionine (By similarity).Swiss-Prot 53.0
34Phosphothreonine (by PKA) (Bysimilarity).Swiss-Prot 53.0
75Phosphothreonine (by CDK5).Swiss-Prot 53.0
198Phosphoserine (By similarity).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

   | Top |

Chromosome

Location

Source

chr17

Promoter: 35035205 - 35037205Agilent_014791

chr17

Promoter: 35036779 - 35038779Agilent_014791

chr17

Promoter: 35035205 - 35037205IlluminaMethylation27

chr17

Promoter: 35036779 - 35038779GSE27584

chr17

Promoter: 35035205 - 35037205GSE27584


Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston Rights Reserved
Site Policies | State of Texas