|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 864 |
Name | RUNX3 |
Synonymous | AML2|CBFA3|PEBP2aC;runt-related transcription factor 3;RUNX3;runt-related transcription factor 3 |
Definition | CBF-alpha-3|PEA2 alpha C|PEA2-alpha C|PEBP2 alpha C|PEBP2-alpha C|SL3-3 enhancer factor 1 alpha C subunit|SL3/AKV core-binding factor alpha C subunit|acute myeloid leukemia 2 protein|acute myeloid leukemia gene 2|core-binding factor subunit alpha-3|core-b |
Position | 1p36 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
|
Regulation From TransFac database |
AML2(h) --> CDKN1A(h) (transactivation) | AML2(h) --> KIR3DL3(h) (DNA binding). | AML2(h) --> KIR2DL3(h) (DNA binding). | AML2(h) --> KIR2DL4(h) (DNA binding). | RUNX3(h) --> AML2(h) (expression). | AML2-isoform1(h) --> CDKN1A(h) (transactivation) | Smad3(m.s.) + AML2-isoform1(h) <==> Smad3(m.s.):AML2-isoform1(h) (binding) | Smad4(m.s.) + AML2-isoform1(h) <==> Smad4(m.s.):AML2-isoform1(h) (binding) | AML2-isoform1(h) + FOXO3a(m.s.) <==> AML2-isoform1(h):FOXO3a(m.s.) (binding) | FOXO3a(h) + AML2-isoform1(h) <==> FOXO3a(h):AML2-isoform1(h) (binding) | AML2-isoform1(h) + p300(h) <==> AML2-isoform1(h):p300(h) (binding) | p300(m.s.) + AML2-isoform1(h) <==> p300(m.s.):AML2-isoform1(h) (binding) | p300(h) + AML2-isoform1(h) <==> p300(h):AML2-isoform1(h) (binding) | AML2-isoform1(h) + 3 acetyl-CoA --p300(m.s.)--> AML2-isoform1(h){aceK148}{aceK186}{aceK192} + 3 CoA (acetylation) | AML2-isoform1(h) + PEBP2beta(m.s.) <==> AML2-isoform1(h):PEBP2beta(m.s.) (binding) | HDAC1(m.s.) + AML2-isoform1(h) <==> HDAC1(m.s.):AML2-isoform1(h) (binding) | AML2-isoform1(h) + hdac2(m.s.) <==> AML2-isoform1(h):hdac2(m.s.) (binding) | AML2-isoform1(h) + HDAC5(m.s.) <==> AML2-isoform1(h):HDAC5(m.s.) (binding) | Smurf-1(m.s.) + AML2-isoform1(h) <==> Smurf-1(m.s.):AML2-isoform1(h) (binding) | AML2-isoform1(h) + Smurf-2(m.s.) <==> AML2-isoform1(h):Smurf-2(m.s.) (binding) | AML2-isoform1(h) + ubiquitin(h) --Smurf-2(m.s.)--> AML2-isoform1(h){ub} (ubiquitination) | AML2-isoform1(h) + ubiquitin(h) --Smurf-1(m.s.)--> AML2-isoform1(h){ub} (ubiquitination) | RUNX3(h) --> AML2-isoform1(h) (expression). | AML2-isoform1(h){aceK} --HDAC5(m.s.)--> AML2-isoform1(h) + acetyl (deacetylation) | AML2-isoform1(h){aceK} --HDAC4(m.s.)--> AML2-isoform1(h) + acetyl (deacetylation) | RUNX3(h) --> AML2-isoform2(h) (expression). |
|---|
Post Transcriptional Modification From dbPTM | | Top | |
There is no record for RUNX3 |
Methylation Profile From DiseaseMeth database | | Top | |
|
Chromosome |
Location |
Source |
|---|---|---|
chr1 |
Promoter: 25128857 - 25130857 | Agilent_014791 |
chr1 |
Promoter: 25163588 - 25165588 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 25128857 - 25130857 | GSE27584 |
chr1 |
Promoter: 25163588 - 25165588 | GSE27584 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:21796503 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:21796503 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:16328045 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:16328045 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:16234815 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:16234815 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:12841866 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:12841866 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:14968123 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:14968123 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:17270239 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:17270239 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:15273736 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:15273736 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:17372756 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:17372756 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:15051926 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:15051926 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:16367921 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:16367921 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:16818622 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:16818622 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:17139617 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:17139617 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:15471559 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:15471559 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:14743205 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:14743205 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:16155404 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:16155404 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:15447999 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:15447999 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:16230397 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:16230397 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:15596045 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:15596045 |
chr1 |
Promoter: 25163588 - 25165588 | PMID:15574200 |
chr1 |
Promoter: 25128857 - 25130857 | PMID:15574200 |