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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 9314 |
Name | KLF4 |
Synonymous | EZF|GKLF;Kruppel-like factor 4 (gut);KLF4;Kruppel-like factor 4 (gut) |
Definition | Krueppel-like factor 4|endothelial Kruppel-like zinc finger protein|epithelial zinc finger protein EZF|gut-enriched krueppel-like factor |
Position | 9q31 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
GKLF-isoform1(h) + p53(h) <==> p53(h):GKLF-isoform1(h) (binding) | GKLF-isoform1(h) --/ HBB(h) (DNA binding; transrepression). | GKLF-isoform1(h) --> CDKN1A(h) (DNA binding; transactivation). | GKLF-isoform1(h) --/ Hbb-b1(m) (DNA binding; transrepression). | KLF4(h) --> GKLF-isoform1(h) (expression). | KLF4(h) --> GKLF(h) (expression). | hsa-miR-7 --/ GKLF(h) (predicted) | HDAC1(h) + GKLFa(h) <==> HDAC1(h):GKLFa(h) (binding) | hdac2(h) + GKLFa(h) <==> hdac2(h):GKLFa(h) (binding) | GKLFa(h) --/ ITGAD(h) (DNA binding; transrepression). | KLF4(h) --> GKLFa(h) (expression). | HDAC1(h) + GKLF(h) <==> HDAC1(h):GKLF(h) (binding) | hdac2(h) + GKLF(h) <==> hdac2(h):GKLF(h) (binding) | GKLF(h) --> ITGAD(h) (DNA binding). | GKLF(h) --> SLC5A6(h) (DNA binding). | GKLF(h) + acetyl-CoA --> GKLF(h){aceK} + CoA (acetylation) | GKLF(h) --/ ENG(h) (transrepression) | GKLF(h) --/ ODC1(h) (transrepression) | GKLF(h) --> LAMA3(h) (transactivation) | GKLF(h) --> Odc1(m) (DNA binding; transactivation). | GKLF(h) --> GHRL(h) (DNA binding). | KLF4(h) --> GKLF(h) (expression). | KLF4(h) --> GKLF-isoform2(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
There is no record for KLF4 |
Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
---|---|---|
chr9 |
Promoter: 109291076 - 109293076 | Agilent_014791 |
chr9 |
Promoter: 109291076 - 109293076 | GSE27584 |
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