Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30068105HIVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS30068106HIVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20062080HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20061501HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20023329HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20038182HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20061739HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20043130HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TCGA Plot Options
Drug Information
GeneCHRM2
DrugBank IDDB00387
Drug NameProcyclidine
Target IDBE0000560
UniProt IDP08172
Regulation Typeantagonist
PubMed IDs17139284; 17016423; 2027917; 2253700; 20624420; 1426023
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Larson EW, Pfenning MA, Richelson E: Selectivity of antimuscarinic compounds for muscarinic receptors of human brain and heart. Psychopharmacology (Berl). 1991;103(2):162-5.@@Waelbroeck M, Camus J, Tastenoy M, Lambrecht G, Mutschler E, Tacke R, Christophe J: Stereoselectivity of procyclidine binding to muscarinic receptor subtypes M1, M2 and M4. Eur J Pharmacol. 1990 Sep 18;189(2-3):135-42.@@Myhrer T: Identification of neuronal target areas for nerve agents and specification of receptors for pharmacological treatment. Neurotoxicology. 2010 Dec;31(6):629-38. doi: 10.1016/j.neuro.2010.07.002. Epub 2010 Jul 17.@@Waelbroeck M, Camus J, Tastenoy M, Mutschler E, Strohmann C, Tacke R, Schjelderup L, Aasen A, Lambrecht G, Christophe J: Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors. Eur J Pharmacol. 1992 Sep 1;227(1):33-42.
GroupsApproved
Direct ClassificationAralkylamines
SMILESOC(CCN1CCCC1)(C1CCCCC1)C1=CC=CC=C1
Pathways
PharmGKBPA164784001
ChEMBLCHEMBL86715