Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30068105HIVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS30068106HIVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20062080HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20061501HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20023329HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20038182HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20061739HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TVIS20043130HPVENSG00000181072.12protein_codingCHRM2NoNo1129A4D1Q0
P08172
Q6SL56
Q6SL59
Q86SJ1
TCGA Plot Options
Drug Information
GeneCHRM2
DrugBank IDDB00376
Drug NameTrihexyphenidyl
Target IDBE0000560
UniProt IDP08172
Regulation Typeantagonist
PubMed IDs1635586; 1994002; 3208836
CitationsBognar IT, Altes U, Beinhauer C, Kessler I, Fuder H: A muscarinic receptor different from the M1, M2, M3 and M4 subtypes mediates the contraction of the rabbit iris sphincter. Naunyn Schmiedebergs Arch Pharmacol. 1992 Jun;345(6):611-8.@@Dorje F, Wess J, Lambrecht G, Tacke R, Mutschler E, Brann MR: Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J Pharmacol Exp Ther. 1991 Feb;256(2):727-33.@@Freedman SB, Beer MS, Harley EA: Muscarinic M1, M2 receptor binding. Relationship with functional efficacy. Eur J Pharmacol. 1988 Oct 26;156(1):133-42.
GroupsApproved
Direct ClassificationAralkylamines
SMILESOC(CCN1CCCCC1)(C1CCCCC1)C1=CC=CC=C1
Pathways
PharmGKBPA164747026
ChEMBLCHEMBL1490