Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20045027HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20049925HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20025509HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20049443HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS44014966HTLV-1ENSG00000149295.14protein_codingDRD2NoNo1813P14416
TCGA Plot Options
Drug Information
GeneDRD2
DrugBank IDDB12579
Drug NameJNJ-37822681
Target IDBE0000756
UniProt IDP14416
Regulation Typeantagonist
PubMed IDs22490380
CitationsLanglois X, Megens A, Lavreysen H, Atack J, Cik M, te Riele P, Peeters L, Wouters R, Vermeire J, Hendrickx H, Macdonald G, De Bruyn M: Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia. J Pharmacol Exp Ther. 2012 Jul;342(1):91-105. doi: 10.1124/jpet.111.190702. Epub 2012 Apr 6.
GroupsInvestigational
Direct ClassificationN-benzylpiperidines
SMILESFC1=C(F)C=C(CN2CCC(CC2)NC2=CC=C(N=N2)C(F)(F)F)C=C1
Pathways
PharmGKB
ChEMBLCHEMBL3234237