Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20045027HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20049925HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20025509HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20049443HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS44014966HTLV-1ENSG00000149295.14protein_codingDRD2NoNo1813P14416
TCGA Plot Options
Drug Information
GeneDRD2
DrugBank IDDB00508
Drug NameTriflupromazine
Target IDBE0000756
UniProt IDP14416
Regulation Typeantagonist
PubMed IDs239169; 30137788; 9081563
CitationsHorn AS, Post ML, Kennard O: Dopamine receptor blockade and the neuroleptics, a crystallographic study. J Pharm Pharmacol. 1975 Aug;27(8):553-63. doi: 10.1111/j.2042-7158.1975.tb09506.x.@@Chokhawala K, Stevens L: Antipsychotic Medications .@@Creese I, Burt DR, Snyder SH: Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):223-6. doi: 10.1176/jnp.8.2.223.
GroupsApproved; Vet_approved
Direct ClassificationPhenothiazines
SMILESCN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(C=C2)C(F)(F)F
Pathways
PharmGKBPA451773
ChEMBLCHEMBL570