Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20045027HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20049925HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20025509HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS20049443HPVENSG00000149295.14protein_codingDRD2NoNo1813P14416
TVIS44014966HTLV-1ENSG00000149295.14protein_codingDRD2NoNo1813P14416
TCGA Plot Options
Drug Information
GeneDRD2
DrugBank IDDB04888
Drug NameBifeprunox
Target IDBE0000756
UniProt IDP14416
Regulation Type
PubMed IDs17393144; 17659474
CitationsAuclair AL, Galinier A, Besnard J, Newman-Tancredi A, Depoortere R: Putative antipsychotics with pronounced agonism at serotonin 5-HT1A and partial agonist activity at dopamine D2 receptors disrupt basal PPI of the startle reflex in rats. Psychopharmacology (Berl). 2007 Jul;193(1):45-54. Epub 2007 Mar 29.@@Newman-Tancredi A, Cussac D, Depoortere R: Neuropharmacological profile of bifeprunox: merits and limitations in comparison with other third-generation antipsychotics. Curr Opin Investig Drugs. 2007 Jul;8(7):539-54.
GroupsInvestigational
Direct ClassificationBiphenyls and derivatives
SMILESO=C1NC2=C(O1)C(=CC=C2)N1CCN(CC2=CC(=CC=C2)C2=CC=CC=C2)CC1
Pathways
PharmGKB
ChEMBLCHEMBL218166