Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10013213HBVENSG00000126218.12protein_codingF10NoNo2159P00742
Q5JVE7
Q5JVE8
TVIS10020895HBVENSG00000126218.12protein_codingF10NoNo2159P00742
Q5JVE7
Q5JVE8
TVIS30020164HIVENSG00000126218.12protein_codingF10NoNo2159P00742
Q5JVE7
Q5JVE8
TCGA Plot Options
Drug Information
GeneF10
DrugBank IDDB06228
Drug NameRivaroxaban
Target IDBE0000216
UniProt IDP00742
Regulation Typeantagonist
PubMed IDs20424181; 20135071; 10592235
CitationsMelillo SN, Scanlon JV, Exter BP, Steinberg M, Jarvis CI: Rivaroxaban for thromboprophylaxis in patients undergoing major orthopedic surgery. Ann Pharmacother. 2010 Jun;44(6):1061-71. doi: 10.1345/aph.1M681. Epub 2010 Apr 27.@@Ufer M: Comparative efficacy and safety of the novel oral anticoagulants dabigatran, rivaroxaban and apixaban in preclinical and clinical development. Thromb Haemost. 2010 Mar;103(3):572-85. doi: 10.1160/TH09-09-0659. Epub 2010 Feb 2.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsApproved
Direct ClassificationPhenylmorpholines
SMILESClC1=CC=C(S1)C(=O)NC[C@H]1CN(C(=O)O1)C1=CC=C(C=C1)N1CCOCC1=O
Pathways
PharmGKB
ChEMBLCHEMBL198362