Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10013213HBVENSG00000126218.12protein_codingF10NoNo2159P00742
Q5JVE7
Q5JVE8
TVIS10020895HBVENSG00000126218.12protein_codingF10NoNo2159P00742
Q5JVE7
Q5JVE8
TVIS30020164HIVENSG00000126218.12protein_codingF10NoNo2159P00742
Q5JVE7
Q5JVE8
TCGA Plot Options
Drug Information
GeneF10
DrugBank IDDB13998
Drug NameLonoctocog alfa
Target IDBE0000216
UniProt IDP00742
Regulation Typeactivator
PubMed IDs13801371; 14285227; 236567; 6436416; 11891806
CitationsBLATRIX C, SOULIER JP: [Preparation of a fraction rich in prothrombin, proconvertin, Stuart factor and antihemophilic factor B (P.P.B. fraction)]. Pathol Biol (Paris). 1959 Dec;7:2477-86.@@LUNDBLAD RL, DAVIE EW: THE ACTIVATION OF STUART FACTOR (FACTOR X) BY ACTIVATED ANTIHEMOPHILIC FACTOR (ACTIVATED FACTOR 8). Biochemistry. 1965 Jan;4:113-20.@@Radnoff OD, Saito H: Inhibition of Hageman factor, plasma thromboplastin antecedent, thrombin and other clotting factors by phenylglyoxal hydrate (38500). Proc Soc Exp Biol Med. 1975 Jan;148(1):177-82.@@Orthner CL: Characterization of proteases in AHF concentrates: effect on factor VIII:von Willebrand protein as assessed by high-pressure gel permeation chromatography. J Lab Clin Med. 1984 Nov;104(5):816-28.@@Freedman J, Mody M, Lazarus AH, Dewar L, Song S, Blanchette VS, Garvey MB, Ofosu FA: Platelet activation and hypercoagulability following treatment with porcine factor VIII (HYATE:C). Am J Hematol. 2002 Mar;69(3):192-9.
GroupsApproved; Investigational
Direct Classification
SMILES
Pathways
PharmGKB
ChEMBL