| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013213 | HBV | ENSG00000126218.12 | protein_coding | F10 | No | No | 2159 | P00742 Q5JVE7 Q5JVE8 |
| TVIS10020895 | HBV | ENSG00000126218.12 | protein_coding | F10 | No | No | 2159 | P00742 Q5JVE7 Q5JVE8 |
| TVIS30020164 | HIV | ENSG00000126218.12 | protein_coding | F10 | No | No | 2159 | P00742 Q5JVE7 Q5JVE8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | F10 |
|---|---|
| DrugBank ID | DB01109 |
| Drug Name | Heparin |
| Target ID | BE0000216 |
| UniProt ID | P00742 |
| Regulation Type | inhibitor |
| PubMed IDs | 17118432; 17004727; 11369259; 3155697 |
| Citations | Ignjatovic V, Summerhayes R, Gan A, Than J, Chan A, Cochrane A, Bennett M, Horton S, Shann F, Lane G, Ross-Smith M, Monagle P: Monitoring Unfractionated Heparin (UFH) therapy: which Anti-Factor Xa assay is appropriate? Thromb Res. 2007;120(3):347-51. Epub 2006 Nov 21.@@Patey SJ, Edwards EA, Yates EA, Turnbull JE: Heparin derivatives as inhibitors of BACE-1, the Alzheimer's beta-secretase, with reduced activity against factor Xa and other proteases. J Med Chem. 2006 Oct 5;49(20):6129-32.@@Rezaie AR: Heparin-binding exosite of factor Xa. Trends Cardiovasc Med. 2000 Nov;10(8):333-8.@@Rosenberg RD: Role of heparin and heparinlike molecules in thrombosis and atherosclerosis. Fed Proc. 1985 Feb;44(2):404-9. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | |
| Pathways | Fc Epsilon Receptor I Signaling in Mast Cells; Heparin Action Pathway |
| PharmGKB | PA449855 |
| ChEMBL | CHEMBL1909300 |
