| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013213 | HBV | ENSG00000126218.12 | protein_coding | F10 | No | No | 2159 | P00742 Q5JVE7 Q5JVE8 |
| TVIS10020895 | HBV | ENSG00000126218.12 | protein_coding | F10 | No | No | 2159 | P00742 Q5JVE7 Q5JVE8 |
| TVIS30020164 | HIV | ENSG00000126218.12 | protein_coding | F10 | No | No | 2159 | P00742 Q5JVE7 Q5JVE8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | F10 |
|---|---|
| DrugBank ID | DB00100 |
| Drug Name | Coagulation Factor IX (Recombinant) |
| Target ID | BE0000216 |
| UniProt ID | P00742 |
| Regulation Type | activator |
| PubMed IDs | 1391956; 8083242; 9079657; 10933803; 10919405; 11752352; 659613 |
| Citations | Worfolk LA, Robinson RA, Tracy PB: Factor Xa interacts with two sites on monocytes with different functional activities. Blood. 1992 Oct 15;80(8):1989-97.@@Jones KC, Mann KG: A model for the tissue factor pathway to thrombin. II. A mathematical simulation. J Biol Chem. 1994 Sep 16;269(37):23367-73.@@Ambrosini G, Plescia J, Chu KC, High KA, Altieri DC: Activation-dependent exposure of the inter-EGF sequence Leu83-Leu88 in factor Xa mediates ligand binding to effector cell protease receptor-1. J Biol Chem. 1997 Mar 28;272(13):8340-5.@@London FS, Walsh PN: Zymogen factor IX potentiates factor IXa-catalyzed factor X activation. Biochemistry. 2000 Aug 15;39(32):9850-8.@@Scandella DH: Properties of anti-factor VIII inhibitor antibodies in hemophilia A patients. Semin Thromb Hemost. 2000;26(2):137-42.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Di Scipio RG, Kurachi K, Davie EW: Activation of human factor IX (Christmas factor). J Clin Invest. 1978 Jun;61(6):1528-38. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164744952 |
| ChEMBL |
