| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20062394 | HPV | ENSG00000133742.14 | protein_coding | CA1 | No | No | 759 | P00915 |
| TVIS44045853 | HTLV-1 | ENSG00000133742.14 | protein_coding | CA1 | No | No | 759 | P00915 |
| TVIS44045852 | HTLV-1 | ENSG00000133742.14 | protein_coding | CA1 | No | No | 759 | P00915 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CA1 |
|---|---|
| DrugBank ID | DB00869 |
| Drug Name | Dorzolamide |
| Target ID | BE0000267 |
| UniProt ID | P00915 |
| Regulation Type | inhibitor |
| PubMed IDs | 8070313; 9029437; 8875343 |
| Citations | Hasegawa T, Hara K, Hata S: Binding of dorzolamide and its metabolite, N-deethylated dorzolamide, to human erythrocytes in vitro. Drug Metab Dispos. 1994 May-Jun;22(3):377-82.@@Maren TH, Conroy CW, Wynns GC, Levy NS: Ocular absorption, blood levels, and excretion of dorzolamide, a topically active carbonic anhydrase inhibitor. J Ocul Pharmacol Ther. 1997 Feb;13(1):23-30.@@Sugrue MF: The preclinical pharmacology of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor. J Ocul Pharmacol Ther. 1996 Fall;12(3):363-76. |
| Groups | Approved |
| Direct Classification | 2,3,5-trisubstituted thiophenes |
| SMILES | CCN[C@H]1C[C@H](C)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O |
| Pathways | |
| PharmGKB | PA164748765 |
| ChEMBL | CHEMBL218490 |
